Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, monohydrate, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- - Names and Identifiers
Name | cholic acid sodium hydrate
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Synonyms | SODIUM CHOLATE HYDRATE cholic acid sodium hydrate CHOLIC ACID SODIUM SALT, HYDRATE CHOLALIC ACID SODIUM SALT HYDRATE Cholicacid,sodiumsalt,monohydrate SODIUM CHOLATE MONOHYDRATE, PURIFIED 3ALPHA, 7ALPHA, 12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OIC ACID SODIUM SALT, HYDRATE Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, monohydrate, (3.alpha.,5.beta.,7.alpha.,12.alpha.)-
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CAS | 73163-53-8
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EINECS | 206-643-5 |
InChI | InChI=1/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1 |
Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, monohydrate, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- - Physico-chemical Properties
Molecular Formula | C24H41NaO6
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Molar Mass | 448.57 |
Solubility | H2O: 1M at20°C, clear, yellow |
Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, monohydrate, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- - Risk and Safety
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-9 |
Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, monohydrate, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- - Introduction
Cholic acid sodium hydrate (hydrate) is an organic compound with the chemical formula C24H39NaO5 · xH2O. It is a kind of bile acid and is one of the main components in bile.
The cholic acid sodium hydrate has the following properties:
1. Appearance: colorless or white crystalline powder;
2. Solubility: Soluble in water and alcohol solvents, insoluble in non-polar solvents such as ether;
3. chemical reaction: with similar properties with other acids, can react with alkali to generate the corresponding salt.
The main uses of cholic acid sodium hydrate include:
1. Pharmaceutical preparation: cholic acid sodium hydrate can be used as the raw material of bile acid in drugs, and is often used in the treatment of hepatobiliary diseases;
2. cosmetics: cholic acid sodium hydrate can be used as a surfactant in cosmetics, with the effect of cleaning and skin conditioning;
3. biochemical research: cholic acid sodium hydrate can be used as a reagent for bile acid analysis and cholesterol metabolism research in biochemical experiments.
The preparation of cholic acid sodium hydrate is generally divided into two steps:
1. Extract bile from the gallbladder of cattle, sheep or pigs;
2. Through multiple crystallization and purification, the sodium salt of bile acid is finally obtained, and it is crystallized with an appropriate amount of water to form a hydrate of cholic acid sodium hydrate.
Note the following safety information when using the cholic acid sodium hydrate:
1. cholic acid sodium hydrate is an irritant, which should be washed with clean water immediately when contacting eyes, skin or inhaling. If not, seek medical treatment immediately;
2. Do not use cholic acid sodium hydrate in the human body without authorization;
3. in storage and use, should avoid contact with the oxidant, avoid fire.
To sum up, cholic acid sodium hydrate is an organic compound with certain medicinal and cosmetic uses. Its preparation method is relatively complicated, and safety needs to be paid attention to when using it.
Last Update:2024-04-09 19:05:52