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Cinnamic acid, p-hydroxy-, methyl ester (8CI)

Methyl 4-hydroxycinnamate

CAS: 3943-97-3

Molecular Formula: C10H10O3

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Cinnamic acid, p-hydroxy-, methyl ester (8CI) - Names and Identifiers

Name Methyl 4-hydroxycinnamate
Synonyms AI3-31901
NSC 154578
methyl coumarate
METHYL 4-COUMARATE
Methyl p-coumarate
methyl 3-hydroxycinnamate
Methyl 4-hydroxycinnamate
METHYL P-HYDROXYCINNAMATE
4-Coumaric acid methyl ester
methyl 3-(4-hydroxyphenyl)acrylate
METHYL 3-(4-HYDROXYPHENYL)ACRYLATE
p-Hydroxycinnamic acid methyl ester
methyl (2Z)-3-(4-hydroxyphenyl)acrylate
methyl 3-(4-hydroxyphenyl)prop-2-enoate
methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Cinnamic acid, p-hydroxy-, methyl ester (8CI)
(E)-3-(4-hydroxyphenyl)-2-methyl-2-propenoate
3-(4-hydroxyphenyl)prop-2-enoic acid methyl ester
2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester (9CI)
CAS 3943-97-3
EINECS 223-531-1
InChI InChI=1/C10H10O3/c1-13-10(12)7-4-8-2-5-9(11)6-3-8/h2-7,11H,1H3/b7-4+

Cinnamic acid, p-hydroxy-, methyl ester (8CI) - Physico-chemical Properties

Molecular FormulaC10H10O3
Molar Mass178.18
Density1?+-.0.06 g/cm3(Predicted)
Melting Point144-145°
Boling Point306.6±17.0 °C(Predicted)
Flash Point132.8°C
Vapor Presure0.000421mmHg at 25°C
AppearanceWhite crystal
pKa8.82±0.13(Predicted)
Storage ConditionInert atmosphere,Room Temperature
Refractive Index1.592

Cinnamic acid, p-hydroxy-, methyl ester (8CI) - Risk and Safety

Hazard ClassIRRITANT

Cinnamic acid, p-hydroxy-, methyl ester (8CI) - Reference

Reference
Show more
1. [IF=2.406] Fu Zhilei et al."Biochemical characterization of a novel feruloyl esterase from Burkholderia pyrrocinia B1213 and its application for hydrolyzing wheat bran."3 Biotech. 2022 Jan;12(1):1-12
2. [IF=3.645] Lewen Xiong et al."Study on phenolic acids of Lonicerae japonicae Flos based on ultrahigh performance liquid chromatography-tandem mass spectrometry combined with multivariate statistical analysis."JOURNAL OF SEPARATION SCIENCE

Cinnamic acid, p-hydroxy-, methyl ester (8CI) - Reference Information

biological activity Methyl p-coumarate (Methyl 4-hydroxyxinnamate), an esterified derivative of p-coumaric acid (pCA) isolated from flowers longifolia by Trixis michuacana var. Methyl p-coumarate inhibits melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also had a strong in vitro inhibitory effect on Alternaria and other pathogens.
NIST chemical information information provided by: webbook.nist.gov (external link)
Last Update:2024-04-09 15:16:37
Cinnamic acid, p-hydroxy-, methyl ester (8CI)
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Cinnamic acid, p-hydroxy-, methyl ester (8CI)
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