Ciprofloxacin EP IMpurity B

Ciprofloxacin EP IMpurity B - Names and Identifiers

Name	1-Cyclopropyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic Acid (Desfluoro Compound)
Synonyms	Desfluorociprofloxacin Ciprofloxacin EP Imp B Ciprofloxacin EP IMpurity B Ciprofloxacin impurity B (EP) Ciprofloxacin EP Impurity B HCl Desfluroenrofloxacin Hydrochloride Ciprofloxacin Impurity 2(Ciprofloxacin EP Impurity B) 1-Cyclopropyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 1-Cyclopropyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic Acid (Desfluoro Compound)
CAS	93107-11-0

Ciprofloxacin EP IMpurity B - Physico-chemical Properties

Molecular Formula	C17H19N3O3
Molar Mass	313.35
Density	1.408±0.06 g/cm3(Predicted)
Boling Point	568.5±50.0 °C(Predicted)
pKa	6.51±0.41(Predicted)
Storage Condition	2-8°C

Ciprofloxacin EP IMpurity B - Introduction

Ciprofloxacin hydrochloride impurity B(EP), chemical name is 1-cyclopropyl -4-oxo -7-(piperazin -1-yl)-1, 4-Dihydroquinoline-3-carboxylic acid (defluorinated compound), is an impurity of compound purity lower than Ciprofloxacin. Because it is a degradant of ciprofloxacin, its properties and uses are similar to ciprofloxacin.

ciprofloxacin hydrochloride impurity B(EP) has the following properties:
-Appearance: white or off-white crystalline solid;
-Melting point: About 241-246 degrees Celsius.

ciprofloxacin hydrochloride impurity B(EP) use:
This impurity is mainly used for quality control in ciprofloxacin preparations, and is used in related research and quality analysis.

ciprofloxacin hydrochloride impurity B(EP) preparation method:
This compound is usually a by-product formed during the preparation of ciprofloxacin. The preparation method includes the steps of oxidation, cleavage and fluoride ion reaction.

Safety information for ciprofloxacin hydrochloride impurity B(EP):
The toxicity and safety information of this compound is relatively limited because it is usually present as an impurity of ciprofloxacin, and its dose should be relatively low in the formulation. However, anyone who uses or handles the compound in the laboratory should follow safe operating procedures and ensure appropriate personal protective measures, such as the use of laboratory gloves, eye and face protection, etc.

Last Update：2024-04-09 21:04:16