Clevidipine Impurity 11 - Names and Identifiers
Clevidipine Impurity 11 - Physico-chemical Properties
Molecular Formula | C15H13Cl2NO2
|
Molar Mass | 310.18 |
Density | 1.280±0.06 g/cm3(Predicted) |
Boling Point | 376.0±42.0 °C(Predicted) |
pKa | 3.41±0.19(Predicted) |
Storage Condition | -20℃ |
Clevidipine Impurity 11 - Introduction
methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate(methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate) is an organic compound. Here is the relevant information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C17H16Cl2N2O2
-Molecular weight: 355.23g/mol
-Melting point: 85-87 ° C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dimethyl ether, insoluble in water.
Use:
- methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate has no specific use, but can be used as a synthetic intermediate in pharmaceutical or other organic synthesis fields.
Method:
The preparation method of methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate can be carried out by the following steps:
1. First, 2,3-dichlorobenzyl alcohol is reacted with 2,6-lutidine to generate 2,3-dichlorophenyl 2,6-lutidine alcohol.
2. Then, 2,3-dichlorophenyl 2,6-lutidine alcohol is reacted with formic acid and sulfonyl chloride to give methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate.
Safety Information:
Specific safety and toxicological profile data for-methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate may be lacking and should be used with caution.
-Appropriate personal protective measures should be taken during operation, such as wearing chemical protective gloves and goggles.
-Proper laboratory procedures should be followed and chemical handling guidelines should be followed.
-Since the toxicity of methyl 4-(2,3-dichlorophenyl)-2,6-dimethylnicotinate is unknown, avoid exposure to skin, eyes, respiratory system, etc.
Last Update:2024-04-10 22:29:15