Crizotinib InterMediate
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
CAS: 330156-50-8
Molecular Formula: C8H7Cl2FO
Crizotinib InterMediate - Names and Identifiers
| Name | (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol |
| Synonyms | 100968 Crizotinib Impurity 5 Crizotinib InterMediate (R)-1-2,6-dichloro-3-fluorophenylethanol (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol (1R)-1-(2,6-dichloro-3-fluorophenyl)ethanol (R)-2,6-Dichloro-3-fluoro-alpha-methylbenzyl Alcohol BenzeneMethanol,2,6-dichloro-3-fluoro-a-Methyl-, (aR)- Benzenemethanol, 2,6-dichloro-3-fluoro-α-methyl-, (αR)- benzeneMethanol, 2,6-dichloro-3-fluoro-α-Methyl-, (alphaR)- 6-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid |
| CAS | 330156-50-8 |
| EINECS | 808-063-3 |
| InChI | InChI=1/C8H7Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-4,12H,1H3/t4-/m1/s1 |
| InChIKey | JAOYKRSASYNDGH-SCSAIBSYSA-N |
Crizotinib InterMediate - Physico-chemical Properties
| Molecular Formula | C8H7Cl2FO |
| Molar Mass | 209.04 |
| Density | 1.406 |
| Melting Point | 41.0 to 45.0 °C |
| Boling Point | 261 °C |
| Flash Point | 112 °C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.00589mmHg at 25°C |
| Appearance | White solid |
| Color | White to Almost white |
| pKa | 13.30±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.546 |
| MDL | MFCD09863794 |
Crizotinib InterMediate - Risk and Safety
| Hazard Class | IRRITANT |
Crizotinib InterMediate - Introduction
(R)-1-(2,-) ethanol is an organic compound with the chemical formula C8H8Cl2F2O. Its molecular structure contains a chiral center, so there are two stereoisomers (R) and (S).
(R)-1-(2,) ethanol is usually a colorless liquid with low solubility. It is an aryl alcohol with certain chemical activity.
The compound has certain uses in the field of medicine. It can be used as a drug intermediate for the synthesis of some specific drug molecules. Due to its chiral properties, it can be used to synthesize compounds with specific stereochemical properties, which is very important for drug development.
(R)-1-(2,) ethanol can be prepared by chemical synthesis. A commonly used synthesis method is to react 2,6-dichloro-3-fluorobenzoic acid with ethanol, which is catalyzed by acid or base to produce the desired alcohol compound.
(R)-1-(2,) ethanol is usually a colorless liquid with low solubility. It is an aryl alcohol with certain chemical activity.
The compound has certain uses in the field of medicine. It can be used as a drug intermediate for the synthesis of some specific drug molecules. Due to its chiral properties, it can be used to synthesize compounds with specific stereochemical properties, which is very important for drug development.
(R)-1-(2,) ethanol can be prepared by chemical synthesis. A commonly used synthesis method is to react 2,6-dichloro-3-fluorobenzoic acid with ethanol, which is catalyzed by acid or base to produce the desired alcohol compound.
Last Update：2024-04-09 20:49:11
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Product Name: (R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethanol Visit Supplier Webpage Request for quotation
CAS: 330156-50-8
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