Cyclo(D-phenylalanyl-L-prolyl) - Names and Identifiers
Name | Cyclo(Phe-Pro)
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Synonyms | Cyclo(Phe-Pro) Cyclo(D-phenylalanyl-L-prolyl) Hexahydro-3-(phenylmethyl) pyrrolo [1,2-a] pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)- 3-(Phenylmethyl)-2,3,6,7,8,8A-hexahydropyrrolo(2,1-F)pyrazine-1,4-dione Pyrrolo(2,1-F)pyrazine-1,4-dione, 2,3,6,7,8,8A-hexahydro-3-(phenylmethyl)-
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CAS | 14705-60-3
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Cyclo(D-phenylalanyl-L-prolyl) - Physico-chemical Properties
Molecular Formula | C14H16N2O2
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Molar Mass | 244.29 |
Density | 1.26±0.1 g/cm3(Predicted) |
Boling Point | 509.5±39.0 °C(Predicted) |
pKa | 13.21±0.40(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Bioactive Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that inhibits polyubiquitination by RIG-I through a specific interaction with RIG-I, and IRF-3 inhibition of activation and type I interferon production. Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) enhances susceptibility to HCV and influenza Virus. |
Cyclo(D-phenylalanyl-L-prolyl) - Introduction
Cyclo(Phe-Pro), abbreviated as Cyclo(Phe-Pro), is an organic compound. The following is a description of some properties, uses, methods and safety information about Cyclo(Phe-Pro):
Nature:
Cyclo(Phe-Pro) is a solid with a high melting point and stability. It is very stable and does not easily decompose at room temperature. Its molecular structure contains phenyl and pyrrolo [1,2-a] pyrazine -1, 4-dione ring structure.
Use:
Cyclo(Phe-Pro) has a wide range of applications in the field of pharmacy and biochemistry. It is used as a model compound to study the folding, structure and function of peptides and proteins. In addition, it can also be used as a raw material for antibacterial and antiviral agents.
Method:
Cyclo(Phe-Pro) can be prepared synthetically. A common method of preparation is to obtain Cyclo(Phe-Pro) by synthetic peptide methods. First, the complete molecule of the two parts of phenyl and pyrrolo [1,2-a] pyrazine -1,4-Dione is synthesized, and then the cyclization reaction is carried out by appropriate reaction conditions and catalysts, the result is Cyclo(Phe-Pro).
Safety Information:
Regarding the safety information of Cyclo(Phe-Pro), no special toxicity or harmfulness has been found at present. However, as a chemical substance, it is still necessary to comply with general safety practices when using it, such as wearing gloves, eye and respiratory protection equipment, and avoiding inhalation, intake or contact.
Last Update:2024-04-09 21:54:55