Cyclopropanamine, 1-(2-chloro-4-fluorophenyl)-

Cyclopropanamine, 1-(2-chloro-4-fluorophenyl)- - Names and Identifiers

Name	1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride
Synonyms	1-(2-Chloro-4-fluorophenyl)cyclopropanamine Cyclopropanamine, 1-(2-chloro-4-fluorophenyl)- 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride
CAS	920501-75-3

Cyclopropanamine, 1-(2-chloro-4-fluorophenyl)- - Physico-chemical Properties

Molecular Formula	C9H9ClFN
Molar Mass	185.626
Storage Condition	2-8℃

Cyclopropanamine, 1-(2-chloro-4-fluorophenyl)- - Introduction

1-(2-chroo-4-fluorophenyl) cyclopropan-1-amine is an organic compound with the chemical formula C9H10ClF N · HCl. It is a colorless crystalline solid that is stable at ambient temperature.

The compound has a wide range of uses in the field of medicine. It is a selective diphenylethylamine reuptake inhibitor and is used as an intermediate for antidepressant drugs. It is associated with the reuptake of the neurotransmitter norepinephrine, which improves mood and mental state by increasing its concentration in the synaptic cleft.

The method for preparing 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride is mainly achieved by ammoniating p-chlorofluorobenzoate. The specific synthetic route includes the following steps: first, the chlorofluorobenzoate is reacted with ammonia under suitable reaction conditions to generate the intermediate chlorofluorobenzoate amide, cyclopropanation of the intermediate p-chlorofluorobenzoate amide was carried out to produce 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride; Finally, the obtained 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride was salted with hydrochloric acid, 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride was obtained.

For safety information, use caution when using 1-(2-chloro-4-fluorophenyl)cyclopropan-1-amine of hydrochloride. It is a potentially irritating compound that may cause irritation to the eyes, skin and respiratory tract. When handling, wear appropriate personal protective equipment to avoid inhalation of dust and direct skin contact. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from fire and flammable materials.

Last Update：2024-04-09 21:01:54