Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-rel- - Names and Identifiers
Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-rel- - Physico-chemical Properties
Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-rel- - Introduction
Trans-2-(3,4-difluorophenyl) cyclopropanoic acid is an organic compound with the chemical formula C10H7F2COOH and the structural formula CF3C6HF(COOH). The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: About 118-120 ° C
-Boiling point: About 349-351 ° C
-Solubility: Soluble in organic solvents such as ether, chloroform and acetone, insoluble in water
Use:
-trans-2-(3,4-difluorophenyl) cyclopropanoic acid is widely used as an organic synthesis intermediate in the field of drug synthesis and pesticide synthesis.
-It can be used to synthesize biologically active compounds, such as compounds with anti-cancer, antibacterial or anti-inflammatory properties.
Method:
trans-2-(3,4-difluorophenyl) cyclopropanoic acid can be synthesized by the following steps:
1. Reacting 3,4-difluorophenyl propene with malonic acid to generate 3,4-difluorophenyl malonic acid.
2.3,4-difluorophenyl malonic acid is heated and dehydrated to generate trans -2-(3,4-difluorophenyl) cyclopropanoic acid.
Safety Information:
-trans-2-(3,4-difluorophenyl) cyclopropanoic acid is less toxic, but it still needs to be handled carefully.
-During operation, avoid direct contact with skin, eyes or clothing entrance.
-During handling and storage, appropriate protective measures need to be taken to ensure the safety of personnel.
-Prohibit the trans -2-(3,4-difluorophenyl) cyclopropanoic acid mixed with oxidants or strong acids, strong bases and other substances to avoid dangerous reactions.
-Use it in a well-ventilated environment and avoid inhaling its vapor.
Last Update：2024-04-09 02:00:52