D & C Red no. 28
Phloxine B
CAS: 18472-87-2
Molecular Formula: C20H2Br4Cl4Na2O5
D & C Red no. 28 - Names and Identifiers
| Name | Phloxine B |
| Synonyms | Cyanosine Phloxin B C.I. 45410 Phloxine B Phloxime B Eosin Blue Acid Red 92 C.I. Acid Red 92 3,4,5,6-tetrachloro-2-(1,4,5,8-tetrabromo-6-hydroxy-3-oxoxanthen-9-yl)benzoic acid disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate |
| CAS | 18472-87-2 |
| EINECS | 242-355-6 |
| InChI | InChI=1/C20H4Br4Cl4O5.2Na/c21-5-1-3-7(8-9(20(31)32)13(26)15(28)14(27)12(8)25)4-2-6(22)17(30)11(24)19(4)33-18(3)10(23)16(5)29;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2 |
D & C Red no. 28 - Physico-chemical Properties
| Molecular Formula | C20H2Br4Cl4Na2O5 |
| Molar Mass | 829.63 |
| Melting Point | >250°C |
| Boling Point | 747.3°C at 760 mmHg |
| Flash Point | 405.8°C |
| Vapor Presure | 1.85E-23mmHg at 25°C |
| Appearance | Form Powder/Solid, color Red Brown |
| PH | 9.7 (1g/l, H2O, 20℃) |
| Storage Condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| MDL | MFCD00070627 |
| Physical and Chemical Properties | Properties Fluorescent pink is red to dark reddish brown particles or powder. Melting point 76~79 ℃. No smell. Soluble in water and ethanol, orange-red, yellow-green fluorescence in aqueous solution. Soluble in glycerin and propylene glycol, insoluble in grease and ether. Poor light resistance, better heat resistance (105 ℃), stable under alkaline conditions, and precipitate when exposed to acid. |
| Use | Used as a biological stain, etc |
D & C Red no. 28 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 2 |
| RTECS | LM5900000 |
| HS Code | 32041200 |
| Toxicity | LD50 orally in Rabbit: 2870 mg/kg |
D & C Red no. 28 - Upstream Downstream Industry
| Raw Materials | Formaldehyde Resorcinol Melamine p-Toluenesulfonamide Tetrachlorophthalic anhydride Tetrachlorofluorescein Tetrachlorophthalic anhydride Resorcinol Chlorthal |
| Downstream Products | Acid Red 94 |
D & C Red no. 28 - Reference
| Reference Show more | Note: Our company can only provide some information for some products. Our company does not guarantee the authority of the information provided. It is only for customers' reference and research. Purpose: This product is only for scientific research and cannot be used for other purposes. (The following uses are for reference only) Biological staining. Adsorption indicator. Fluorescent indicator. Verification of mercury. Used for Mallory's fluorescent pink-methylene blue dyeing; Kreyberg's method is used for keratin and mucus storage conditions: -20 ℃ solubility: dissolved in water as blue-red solution with slightly dark green fluorescence, dissolved in ethanol as blue-red solution with brick-red fluorescence, brown-yellow precipitate is generated when heated in hydrochloric acid, blue precipitate is generated in sodium hydroxide, yellow solution in concentrated sulfuric acid, and no change occurs when heated, when diluted, yellow-red precipitate is produced. Appearance: Brick red or brownish red to dark brown powder Fluorescent pink B has been proved to be a Gram dye substitute. Studies have found that it can inhibit the growth of methicillin-resistant Staphylococcus aureus. Fluorescent peach B can stimulate and inhibit the channel activity of wild-type cystic fibrosis transmembrane conduction regulator (CFTR). It has antibacterial effects. Fluorescent peach B staining can be used to distinguish between Gram-positive and Gram-negative bacteria. Ethylene oxide B is a component of xanthate dyes. The stain is mainly used to determine the cell ploidy and temperature sensitivity of Schizosaccharomyces cerevisiae. The color of the solid medium is bright pink. (For reference only) |
D & C Red no. 28 - Nature
| solubility | 100g/l |
| color index | 45410 |
| pH range of acid-base indicator discoloration | NonQ uorescence (2.5) to yellowish-blue Q uorescence (4.0) |
| maximum wavelength (& lambda;max) | 548nm, 510nm |
| BRN | 3887100 |
| biological applications | Detecting proteins; treating microbial infection,parasitic infection,skin,mouth,digestive tract,urinary tract,reproductive tract,respiratory tract,circulatory system,head,neck,endocrine system |
| main applications | Optical waveguides, color filter, lithographic printing plates, display device, visualization of dentaldevice, inks, highlighters, textiles, hair dyes, cosmetics, visualization of dentalplaque, treatment of infectitious diseases, antitumor agents |
| EPA chemical information | Phloxine B (18472-87-2) |
Last Update：2024-04-10 22:29:15
D & C Red no. 28 - Uses and synthesis methods
introduction
fluorescent pink (Phloxine) is also called rose red. Root bark red; Edible red plain color 104-Japanese name, is an artificial organic synthetic pigment. Fluorescent pink is an azo acid dye with a red powder appearance. It is soluble in water as a big red solution, slightly soluble in alcohol and fibrinolytic, and insoluble in other organic solvents. When it comes to concentrated sulfuric acid, it is blue-red, and it is yellowish red after dilution; when it comes to concentrated nitric acid, it is an orange-red solution and then turns orange; when it comes to concentrated hydrochloric acid, it generates a red precipitate and dissolves after dilution.
Preparation
Fluorescent pink can be synthesized from resorcinol and tetrachlorophthalic anhydride to tetrachlorofluorescein, and then brominated.
content analysis
accurately weigh about 1g of the sample, add water to dissolve and dissolve to 100ml, take 50ml as the sample solution, and then measure according to method 3 in the OT-15.
Toxicity
LD50 2.08~3.17 g/kg (mouse, oral).
use
1. orange red pigment for color mixing is widely used in candy, cakes, fish cakes, sausages, confectionery products and biscuits in Japan. Not suitable for beverages, hard candies, etc. with pH below 4.5. The dosage is 5~100mg/kg.
2, used for coloring paint, paint printing, paint, ink, plastic products, stationery, etc.
3. Adsorption indicator for Mallory's fluorescent pink-methylene blue staining; Kreyberg's method is used for keratin and mucus.
4, biological staining, adsorption indicator, fluorescent indicator, verification of mercury.
production method
Tetrachlorofluorescein is synthesized from resorcinol and tetrachlorophthalic anhydride, and then brominated.
category
toxic substances
toxicity classification
Poisoning
acute toxicity
intravenous-mouse LD50: 310 mg/kg
flammability hazard characteristics
Flammable; combustion releases extremely toxic bromide, chloride and sodium oxide fumes
storage and transportation features
The warehouse is ventilated and dry at low temperature; stored separately from oxidants, acids, and food additives
fire extinguishing agent
dry powder, foam, carbon dioxide, sand.
Last Update：2024-04-10 22:29:15
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Product Name: Phloxine B Visit Supplier Webpage Request for quotationCAS: 18472-87-2
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Spot supply
Product Name: Acid Red 92 Visit Supplier Webpage Request for quotationCAS: 18472-87-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: Phloxine B Visit Supplier Webpage Request for quotationCAS: 18472-87-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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Raw Materials for D & C Red no. 28
Downstream Products for D & C Red no. 28