D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone
(-)-Hydroxycitric acid lactone
CAS: 27750-13-6
Molecular Formula: C6H6O7
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone - Names and Identifiers
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone - Physico-chemical Properties
| Molecular Formula | C6H6O7 |
| Molar Mass | 190.11 |
| Density | 1.976 |
| Boling Point | 673.6±55.0 °C(Predicted) |
| Appearance | Solid |
| pKa | 2.40±0.40(Predicted) |
| Storage Condition | 2-8°C，密封，干燥 |
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone - Reference Information
| biological activity | (-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity drug, it is also a popular food supplement for weight loss. (-)-hydroxy citric acid lactone is a potent ATP-citrate lyase inhibitor. (-)-Hydroxycitric acid lactone catalyzes the extracellular cleavage of citrate to oxaloacetate and acetyl-CoA, limiting the availability of acetyl-CoA units required for fatty acid synthesis. |
| Animal Model: | 1-day-old male broiler chickens |
| Dosage: | 1000, 2000, 3000 mg/kg |
| Administration: | Fed for a period of 4 weeks |
| Result: | Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower. |
Last Update：2024-04-09 21:01:54
