Molecular Formula | C83H86Cl2N8O30 |
Molar Mass | 1746.53 |
Density | 1.66±0.1 g/cm3(Predicted) |
Solubility | H2O: soluble10mg/mL |
Appearance | powder |
Color | faintly beige |
pKa | 2.73±0.70(Predicted) |
Storage Condition | -20°C |
WGK Germany | 3 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 0.573 ml | 2.863 ml | 5.726 ml |
5 mM | 0.115 ml | 0.573 ml | 1.145 ml |
10 mM | 0.057 ml | 0.286 ml | 0.573 ml |
5 mM | 0.011 ml | 0.057 ml | 0.115 ml |
overview | dabavan star nucleus hydrochloride is a natural glycopeptide antibiotic ATCC39727 by actinomycetes nonomura (Nonomuraeasp.), mainly composed of PA, PB, A, B0 and B1. At present, the research and production of the mother nucleus of Dabavan hydrochloride has just started. At the same time, due to the complex composition of the microbial fermentation product, the low concentration of the target product, and the complex structure and poor stability, the preparation is difficult. It has become the key to the preparation process of Dabavan. |
application | dabavan star nucleus hydrochloride is a natural glycopeptide antibiotic produced by the ATCC39727 of Actinomycetes Nonomura (Nonomuraeasp.), which can be used to treat bacterial infections. |
biological activity | A40926, the precursor of Dalbavancin, is the second generation glycopeptide antibiotic. A40926 inhibits Gram-positive bacteria and is very effective against Neisseria gonorrhoeae (Neisseria gonorrhoeae). |