Name | Desmopressin Acetate |
Synonyms | ddavp DDAVP DESMORESSIN ACETATE DesmopressinAcetate Desmopressin Acetate DESMOPRESSIN ACETATE DESMOPRESSIN MONOACETATE DESMOPRESSIN ACETATE SALT 1-Deamino-8-D-arginine-vasopressin diacetate 1-deamino-8-d-arginine-vasopressin diacetate 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin diacetate 1-(3-mercaptopropionic acid)-8-d-arginine-vasopressin diacetate |
CAS | 16789-98-3 |
EINECS | 634-101-1 |
InChI | InChI=1/C46H64N14O12S2.2C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;2*1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);2*1H3,(H,3,4) |
Molecular Formula | C48H68N14O14S2 |
Molar Mass | 1129.28 |
Melting Point | 170-172°C (dec.) |
Solubility | Acetic Acid (Slightly), Methanol (Slightly), Water (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | −20°C |
Physical and Chemical Properties | In recent years, a new synthesis of vasopressin substances, namely, the 1-position cysteine and 8-position L-arginine of vasopressin were replaced by β-mercaptopropionic acid and D-arginine, respectively. This product pressor effect is 2000 times smaller than the essence of vasopressin, and antidiuretic effect than natural vasopressin strong and lasting, long half-life 3 times. |
Use | Treatment of massive hemorrhage, diabetes insipidus, urinary incontinence, etc |
Hazard Symbols | Xn - Harmful |
Risk Codes | 20 - Harmful by inhalation |
Safety Description | 36 - Wear suitable protective clothing. |
WGK Germany | 3 |