DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT)

DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT) - Names and Identifiers

Name	Potassium di-tert-butylphosphate
Synonyms	Nsc264063 Di-tert-butyl phosphate di-tert-butyl phosphate POTASSIUM DI-TERT-BUTYLPHOSPHATE Potassium di-tert-butylphosphate di-tert-butyl hydrogen phosphate Di-t-butyl phosphate, potassium salt DI-TERT-BUTYLPHOSPHATE, POTASSIUM SALT Di-tert-butyl phosphate potassium salt DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT) bis(tert-butoxy)phosphinic acid potassium hydride
CAS	33494-80-3
InChI	InChI=1/C8H19O4P/c1-7(2,3)11-13(9,10)12-8(4,5)6/h1-6H3,(H,9,10)/p-1
InChIKey	ZSWXMOQFFWMZQH-UHFFFAOYSA-M

DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT) - Physico-chemical Properties

Molecular Formula	C8H20KO4P
Molar Mass	250.32
Melting Point	247-252°C
Boling Point	252.3°C at 760 mmHg
Flash Point	106.4°C
Vapor Presure	0.00611mmHg at 25°C
Appearance	Powder
Color	white
Storage Condition	2-8°C
MDL	MFCD03840344

DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT) - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
TSCA	No

DI-TERTIARYBUTYL PHOSPHATE (POTASSIUM SALT) - Reference Information

Use

Potassium salt of di-tert-butyl phosphate is a catalyst used in organic synthesis.
Potassium di-tert-butyl phosphate is a catalyst for organic synthesis. It is also used to prepare HIV attachment inhibitor BMS-663068.

Preparation

Combine di-tert-butyl phosphite (40.36mmol) with potassium bicarbonate (24.22mmol) in 35ml of water. The solution was stirred in an ice bath and potassium permanganate (28.25mmole) was added in three equal parts over an hour. The reaction was then allowed to continue for another half hour at room temperature. The decolorized carbon (600mg) was then incorporated as the reaction was heated to 60°C for 15 minutes. The reaction is then vacuum filtered to remove the solid magnesium dioxide. The solids are washed with water several times. The filtrate was then combined with one gram of decolorized carbon and heated at 60°C for another twenty minutes. The solution is filtered again to obtain a colorless solution, and then evaporated in vacuum to obtain a crude potassium salt of di-tert-butyl phosphate.

Last Update：2024-04-10 22:29:15