Overview | The pericarp of the dried sclerotia of poracocos (Schw.)Wolf, a fungus of the family polyporaceae. According to traditional Chinese medicine, poria sweet, light, sex flat, with water wet, spleen and stomach, the efficacy of the heart and mind. At present, studies have shown that Poria Peel has immunomodulatory, anti-tumor, anti-convulsant, antibacterial and anti-inflammatory effects. To study the pharmacodynamics and pharmacokinetics of ethanol extract of poria cocos on nephrotic syndrome, and points out that the dehydromoronic acid, tumoic acid, dehydropachymic acid, pachymic acid is the material basis for the efficacy of the ethanol extract of poria cocos. However, compared with poria cocos, the chemical composition of poria cocos Peel is complex, including polysaccharides, triterpenes, fatty acids, sterols, enzymes, etc, studies have shown that the content of triterpenoids in Poria Peel is much higher than that in the sclerotium of poria cocos. The main active ingredients of the extract of poria Peel are 3 β-hydroxy-landrane 7,9(11),24-triene-21-acid and dehydrodental keto acid, and the effective components in the ethanol extract of poria cocos were significantly different. |