Desoximetasone Impurity 4
8DM Grignard's
CAS: 59796-52-0
Molecular Formula: C22H28O4
Desoximetasone Impurity 4 - Names and Identifiers
Desoximetasone Impurity 4 - Physico-chemical Properties
| Molecular Formula | C22H28O4 |
| Molar Mass | 356.46 |
| Density | 1.25 |
| Melting Point | 253℃ |
| Boling Point | 522.3±50.0 °C(Predicted) |
| pKa | 12.96±0.70(Predicted) |
Desoximetasone Impurity 4 - Introduction
8DM Grignard's is an organometallic compound, also known as octamethylene o-phenanthryl magnesium compound. Its chemical formula is C8H7MgBr, where M represents a metal.
Nature:
8DM Grignard's is a solid substance that can form brown crystals. It is very sensitive to air and water and easily reacts with them. It is soluble in some organic solvents such as ether and tetrahydrofuran at room temperature.
Use:
8DM Grignard's are important intermediates in organic synthesis. Due to its strong basicity and electrophilicity, it is often used to form carbon-carbon bonds and carbon-metal bonds. It can react with many charge-unbalanced organic compounds to form new organic molecules. This makes it an important raw material for the synthesis of new drugs, pesticides and chemicals.
Preparation Method:
The preparation of 8DM Grignard's typically employs Grignard reactions. First, the phenanthrene alcohol is gradually added to the magnesium metal sheet to form the Grignard reagent, and then the 8DM Grignard's are formed by adding magnesium bromide.
Safety Information:
Due to the high reactivity of 8DM Grignard's, extra care should be taken during operation. It is very sensitive to air and water, so it must be operated under inert atmosphere and anhydrous conditions. Wear protective goggles and gloves during operation to avoid direct contact with skin and eyes. At the same time, it is also a flammable substance and should be kept away from open flames and fire sources. If inhaled or ingested, seek medical attention immediately. For more detailed safety information, reference should be made to the safety data sheets of the relevant chemicals.
Nature:
8DM Grignard's is a solid substance that can form brown crystals. It is very sensitive to air and water and easily reacts with them. It is soluble in some organic solvents such as ether and tetrahydrofuran at room temperature.
Use:
8DM Grignard's are important intermediates in organic synthesis. Due to its strong basicity and electrophilicity, it is often used to form carbon-carbon bonds and carbon-metal bonds. It can react with many charge-unbalanced organic compounds to form new organic molecules. This makes it an important raw material for the synthesis of new drugs, pesticides and chemicals.
Preparation Method:
The preparation of 8DM Grignard's typically employs Grignard reactions. First, the phenanthrene alcohol is gradually added to the magnesium metal sheet to form the Grignard reagent, and then the 8DM Grignard's are formed by adding magnesium bromide.
Safety Information:
Due to the high reactivity of 8DM Grignard's, extra care should be taken during operation. It is very sensitive to air and water, so it must be operated under inert atmosphere and anhydrous conditions. Wear protective goggles and gloves during operation to avoid direct contact with skin and eyes. At the same time, it is also a flammable substance and should be kept away from open flames and fire sources. If inhaled or ingested, seek medical attention immediately. For more detailed safety information, reference should be made to the safety data sheets of the relevant chemicals.
Last Update：2024-04-09 21:11:58
