Dexmedetomidine Impurity 47

Dexmedetomidine Impurity 47 - Names and Identifiers

Name	2,3-Dimethylbenzoyl chloride
Synonyms	2,3-diMethyl chloride Dexmedetomidine Impurity 47 2,3-Dimethylbenzoyl chloride Benzoyl chloride, 2,3-dimethyl- benzoyl chloride, 2,3-dimethyl- 2,3-DIMETHYLBENZENE-1-CARBONYL CHLORIDE Benzoyl chloride, 2,3-dimethyl- (6CI,7CI,8CI,9CI)
CAS	21900-46-9
InChI	InChI=1/C9H9ClO/c1-6-4-3-5-8(7(6)2)9(10)11/h3-5H,1-2H3

Dexmedetomidine Impurity 47 - Physico-chemical Properties

Molecular Formula	C9H9ClO
Molar Mass	168.62
Density	1.136±0.06 g/cm3(Predicted)
Melting Point	2°C
Boling Point	122 °C
Flash Point	122-124°C
Vapor Presure	0.0285mmHg at 25°C
Storage Condition	Room Temprature
Sensitive	Moisture Sensitive
Refractive Index	1.5550
MDL	MFCD00045217

Dexmedetomidine Impurity 47 - Risk and Safety

Risk Codes	R34 - Causes burns R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	3265
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

Dexmedetomidine Impurity 47 - Introduction

2,3-Dimethylbenzoyl chloride, chemical formula C9H9ClO, is an organic compound.

Nature:
-Appearance: Colorless to light yellow liquid.
-Melting point: 14-15 degrees Celsius.
-Boiling point: 245-246 degrees Celsius.
-Density: 1.122g/cm³.
-Solubility: Soluble in organic solvents, such as benzene and ether.

Use:
2,3-Dimethylbenzoyl chloride is commonly used as an important reagent in organic synthesis. The main uses include:
-as an intermediate in the synthesis of aromatic acid chloride compounds.
-for the synthesis of drugs, pesticides and other compounds containing acylated structure.
-Used for acylation and arylation reactions in organic synthesis reactions.

Preparation Method:
A common preparation method is to react 2,3-dimethylbenzoic acid with thionyl chloride. Reaction conditions are generally carried out at lower temperatures to avoid side reactions.

Safety Information:
- 2,3-Dimethylbenzoyl chloride is a corrosive substance and should be protected from contact with skin, eyes and respiratory tract. Wear appropriate protective gloves, glasses and respirator during operation.
-During use or storage, avoid contact with oxidants and alkaline substances to prevent dangerous reactions.
-Operate in a well-ventilated place and avoid inhaling its vapor.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When using and handling the compound, follow the relevant safety procedures and regulations.

Last Update：2024-04-09 15:17:57