Dimethyl thiophosphoryl chloride

Dimethyl thiophosphoryl chloride - Names and Identifiers

Name	Dimethylphosphinothioic chloride
Synonyms	Dimethylthiophosphoryl chloride DIMETHYLTHIOPHOSPHINIC CHLORIDE Dimethylthiophosphinic chloride CHLORODIMETHYLPHOSPHINE SULFIDE DIMETHYLPHOSPHINOTHIOYL CHLORIDE Dimethyl thiophosphoryl chloride Dimethylthiophosphinoyl Chloride Dimethylphosphinothioic chloride DIMETHYLPHOSPHINOTHIOIC CHLORIDE Phosphinothioic chloride, dimethyl- Dimethyl thiophosphoryl chloride [UN2267] [Poison] Chlorodimethylphosphine SulfideDimethylphosphinothioyl Chloride
CAS	993-12-4
EINECS	213-606-7
InChI	InChI=1/C2H6ClPS/c1-4(2,3)5/h1-2H3

Dimethyl thiophosphoryl chloride - Physico-chemical Properties

Molecular Formula	C2H6ClPS
Molar Mass	128.56
Density	1.23
Boling Point	69-70 °C (11 mmHg)
Flash Point	105℃
Vapor Presure	11.3mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Almost colorless
Storage Condition	Refrigerator
Refractive Index	1.538-1.541
Physical and Chemical Properties	character: colorless or amber liquid with pungent odor. boiling point 66~67 ℃ relative density 1.32 refractive index 1.4795 flash point 105 ℃ solubility insoluble in water, soluble in ethanol, benzene, chloroform, carbon tetrachloride, ethyl ether, ethyl acetate and other organic solvents. Slightly soluble in hexane.
Use	Used as a pesticide intermediate, used in the production of trimethoprim, insecticide nitrile, 1605, methyl 1605, methamidophos and acephate, methyl pyrimidine and so on

Dimethyl thiophosphoryl chloride - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns R29 - Contact with water liberates toxic gas R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S8 - Keep container dry. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	1760
Hazard Class	8
Packing Group	II

Dimethyl thiophosphoryl chloride - Nature

Open Data Verified Data

colorless or amber liquid with pungent odor. Insoluble in water, soluble in ethanol, benzene, chloroform, carbon tetrachloride, ethyl ether, ethyl acetate and other organic solvents. Slightly soluble in hexane. The relative density was 1. 32. Refractive index 4795. Boiling Point 66~67 degrees C (2kPa). Flash point 105 °c.

Last Update：2024-01-02 23:10:35

Dimethyl thiophosphoryl chloride - Preparation Method

Open Data Verified Data

methanol alkali method methanol and trichlorosulfon were reacted with methanol solution at O ℃ to produce O-methylthiophosphoryl dichloride, and then further reacted with methanol at O ℃ to obtain 0,O-= methylthiophosphoric acid monochloride. The reactants were washed with water and subjected to distillation under reduced pressure to obtain a finished product.
The sodium methoxide method was obtained by the interaction with the phosphorus chloride.
phosphorus pentasulfide method from phosphorus pentasulfide and methanol, 0,O '-methyl dithiophosphate; And then obtained by chlorination.

Last Update：2022-01-01 10:38:13

Dimethyl thiophosphoryl chloride - Use

Open Data Verified Data

pesticide intermediates, used for the preparation of trimethoprim, insecticide and 1605, methyl 1605, methamidophos and acephate, etc. It is also used as a mineral processing collector.

Last Update：2022-01-01 10:38:13

Dimethyl thiophosphoryl chloride - Safety

Open Data Verified Data

This product is toxic. Irritant to eyes, skin and mucous membranes, inhalation or absorption through the skin can cause poisoning. Mild poisoning often cause dizziness, Head Pain, Fatigue, loss of appetite, then Vomit, Diarrhea, numbness of limbs. Severe poisoning will appear Coma, convulsions, incontinence and pulmonary edema and other symptoms, severe central nervous system or circulatory system failure and death. The LD50 for mice was 450mg/kg.
in the process of production, transportation and use, the poison must be prevented from escaping, the workshop should be well ventilated, the production equipment should be sealed, and the operator should wear protective equipment. Splash in the eyes can be washed with water or extended treatment. Wash the skin with soap and water. Oral poisoning with saline or 2% ~ 4% sodium bicarbonate solution gastric lavage.
This product is an intermediate. Can be stored in ceramic or enamel containers. Hazardous materials shall be stored and transported according to regulations.

Last Update：2022-01-01 10:38:14

Dimethyl thiophosphoryl chloride - Reference Information

EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Application	used as pesticide intermediate, used in the production of trimethoprim, chlorfenitrile, 1605, methyl 1605, methamidophos and acephate,

Last Update：2024-09-05 09:57:37