ETHYL (3,4-DICHLOROBENZOYL)ACETATE

Name	3-(3,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
Synonyms	ETHYL (3,4-DICHLOROBENZOYL)ACETATE Ethyl 2-(3,4-dichlorobenzoyl)acetate Ethyl 3-(3,4-dichlorophenyl)-3-oxopropionate ETHYL 3-(3,4-DICHLOROPHENYL)-3-OXOPROPANOATE Benzenepropanoic acid, 3,4-dichloro-b-oxo-, ethyl ester Benzenepropanoic acid, 3,4-dichloro-β-oxo-, ethyl ester 3-(3,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
CAS	53090-43-0

Molecular Formula	C11H10Cl2O3
Molar Mass	261.1
Density	1.319
Boling Point	357.6±32.0 °C(Predicted)
pKa	9.62±0.48(Predicted)
Storage Condition	Sealed in dry,Room Temperature

Introduction	Ethyl 3-(3, 4-dichlorophenyl)-3-oxopropionate is an organic intermediate, and it has been reported in the literature that it can be used to prepare α-ketoamide and its derivatives.
Uses	Ethyl 3-(3, 4-dichlorophenyl)-3-oxopropionate is an organic intermediate, and it has been reported in the literature that it can be used to prepare α-ketoamide and its derivatives.
Preparation	Substituted 3,4-dichlorobenzaldehyde (0.5 mmol), ethyl diazoacetate (0.6 mmol) and ter-BuOK(0.1 mmol) were added to a 10 mL flask with a stir bar. Stir the mixture vigorously at room temperature for 0.5 hours. The reaction progress was monitored by TLC. The resulting mixture was directly separated by silica gel rapid column chromatography to give ethyl 3-(3, 4-dichlorophenyl)-3-oxopropionate.

Last Update：2024-04-09 19:05:11