ETHYL 2-CYANO-2-PHENYLACETATE

ETHYL 2-CYANO-2-PHENYLACETATE - Names and Identifiers

Name	Ethyl phenylcyanoacetate
Synonyms	RARECHEM AK ML 0109 ETHYL PHENYLCYANOACETATE Ethyl phenylcyanoacetate ethyl cyano(phenyl)acetate ETHYL 2-CYANO-2-PHENYLACETATE Ethyl alpha-cyanophenylacetate ethyl (2R)-cyano(phenyl)ethanoate ethyl (2S)-cyano(phenyl)ethanoate Phenylcyanoacetic acid ethyl ester PHENYLCYANOACETIC ACID ETHYL ESTER Ethyl alpha-cyano-alpha-phenylacetate Acetic acid, cyanophenyl-, ethyl ester (2S)-2-cyano-2-phenylacetic acid ethyl ester
CAS	4553-07-5
EINECS	224-921-4
InChI	InChI=1/C11H11NO2/c1-2-14-11(13)10(8-12)9-6-4-3-5-7-9/h3-7,10H,2H2,1H3/t10-/m1/s1

ETHYL 2-CYANO-2-PHENYLACETATE - Physico-chemical Properties

Molecular Formula	C11H11NO2
Molar Mass	189.21
Density	1.09 g/mL at 25 °C (lit.)
Melting Point	115-116 °C
Boling Point	275 °C (lit.)
Flash Point	>110°C
Solubility	Chloroform, DMSO, Methanol (Slightly)
Vapor Presure	0.00523mmHg at 25°C
Appearance	Liquid
Color	Clear colorless to light yellow
BRN	611232
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.5033-1.5053
MDL	MFCD00001866

ETHYL 2-CYANO-2-PHENYLACETATE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21 - Harmful by inhalation and in contact with skin. R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S23 - Do not breathe vapour. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN3276
WGK Germany	3
HS Code	29269095
Hazard Class	6.1
Packing Group	III

ETHYL 2-CYANO-2-PHENYLACETATE - Introduction

Ethyl phenylcyanoacetate(Ethyl phenylcyanoacetate) is an organic compound containing a phenyl group and a cyano group in its chemical structure. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Ethyl phenylcyanoacetate is a colorless to slightly yellow liquid.
-Solubility: It can be dissolved in many organic solvents, such as alcohols, ethers and ketones.
-Melting point: approximately -25°C.
-Boiling point: about 200 ℃.
-Density: Approximately 1.09 g/mL.
-Stability: It is relatively stable at room temperature, but may decompose under high temperature or strong acid conditions.

Use:
Ethyl phenylcyanoacetate has a wide range of applications in the field of organic synthesis, often used as synthetic intermediates. For example, it can be used to synthesize compounds such as pharmaceuticals, pesticides and dyes. It can also be used to prepare some biologically active organic molecules.

Preparation Method:
Ethyl phenylcyanoacetate can be prepared by condensation reaction of ethyl phenylacetate and cyanoacetic acid. In general, ethyl phenylacetate and cyanoacetic acid are reacted under acidic conditions, and the condensation reaction is promoted by acid catalysis.

Safety Information:
-Detailed information on the toxicity and carcinogenicity of Ethyl phenylcyanoacetate is limited, so care must be taken.
-During use, care should be taken to avoid contact with skin and eyes. If you accidentally touch, please rinse immediately with plenty of water and seek help from a doctor.
-Keep away from high temperature, fire and oxidant during use or storage.
-Use appropriate personal protection, such as gloves, safety goggles and protective clothing.

Last Update：2024-04-09 20:49:11