ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE

ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE - Names and Identifiers

Name	Ethyl 3-(trifluoromethyl)crotonate
Synonyms	Ethyl-4,4,4-trifluorbut-2-enoat Ethyl 4,4,4-trifluorobut-2-enoate ETHYL 3-(TRIFLUOROMETHYL)CROTONATE Ethyl 3-(trifluoromethyl)crotonate ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE 3-(Trifluoromethyl)crotonicacidethylester Ethyl 4,4,4-trifluoro-3-Methylbut-2-enoate ethyl 4,4,4-trifluoro-3-methylbut-2-enoate 2-butenoic acid, 4,4,4-trifluoro-, ethyl ester ethyl (2E)-4,4,4-trifluoro-3-methylbut-2-enoate ethyl (2Z)-4,4,4-trifluoro-3-methylbut-2-enoate ethyl 3-(trifluoromethyl)crotonate, cis + trans
CAS	24490-03-7
InChI	InChI=1/C7H9F3O2/c1-3-12-6(11)4-5(2)7(8,9)10/h4H,3H2,1-2H3/b5-4+

ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE - Physico-chemical Properties

Molecular Formula	C7H9F3O2
Molar Mass	182.14
Density	1.157±0.06 g/cm3(Predicted)
Boling Point	129 °C
Flash Point	32°C
Vapor Presure	1.46mmHg at 25°C
BRN	1910081
Storage Condition	Room Temprature
Refractive Index	1.378
MDL	MFCD00040846

ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE - Risk and Safety

Hazard Symbols	F - Flammable
Risk Codes	R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3272
Hazard Note	Flammable
Hazard Class	3
Packing Group	III

ETHYL 3-(TRIFLUOROMETHYL)-2-BUTENOATE - Introduction

Ethyl 3-(trifluoromethyl)crotonate is an organic compound with the chemical formula C7H9F3O2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
Ethyl 3-(trifluoromethyl)crotonate is a colorless liquid with hydrolytic properties. It has a density of 1.336 g/mL and a boiling point of 157-158 ° C.

Use:
The compound is commonly used in organic synthesis. It is useful as an intermediate in the synthesis of biologically active compounds. In addition, it can also be used in the preparation of fungicides, pesticides and pharmaceuticals.

Method:
Ethyl 3-(trifluoromethyl)crotonate can be prepared by the following two-step synthesis:
First, crotonic acid and trifluoromethyl borate are esterified to generate 3-(trifluoromethyl) crotonic acid under acidic conditions;
Next, the obtained 3-(trifluoromethyl) crotonic acid is reacted with ethanol to generate Ethyl 3-(trifluoromethyl)crotonate under the action of an acidic catalyst.

Safety Information:
When using and operating Ethyl 3-(trifluoromethyl)crotonate, pay attention to the following safety precautions:
1. The compound is irritating and should avoid contact with skin, eyes and respiratory tract.
2. Use to wear appropriate protective equipment, such as protective glasses, gloves and protective masks.
3. In the process of operation to maintain good ventilation conditions.
4. Avoid contact with oxidants and strong bases to avoid dangerous reactions.
5. Waste should be disposed of in accordance with local regulations and should not be dumped into sewers or the environment.

Please note that the use and operation of any chemical substances should strictly follow the relevant safety operating procedures and operate under the guidance of experienced personnel.

Last Update：2024-04-09 21:01:54