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Epmedin B

Epmedin B

CAS: 110623-73-9

Molecular Formula: C38H48O19

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Epmedin B - Names and Identifiers

Name Epmedin B
Synonyms Epmedin B
EPIMEDIN B
EPIMEDIN B(PRIMARY STANDARD)
4H-1-Benzopyran-4-one,3-[(6-deoxy-2-O-β-D-xylopyranosyl-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
3-[(6-deoxy-2-O-beta-D-xylopyranosyl-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
3-[(6-Deoxy-2-O-beta-D-xylopyranosyl-alpha-L-mannopyranosyloxy)]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxy-phenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
3-((6-Deoxy-2-O-beta-D-xylopyranosyl-alpha-L-mannopyranosyl)oxy)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
CAS 110623-73-9
InChI InChI=1/C38H48O19/c1-14(2)5-10-18-21(53-37-31(49)28(46)26(44)22(12-39)54-37)11-19(40)23-27(45)34(32(55-33(18)23)16-6-8-17(50-4)9-7-16)56-38-35(29(47)24(42)15(3)52-38)57-36-30(48)25(43)20(41)13-51-36/h5-9,11,15,20,22,24-26,28-31,35-44,46-49H,10,12-13H2,1-4H3/t15-,20+,22+,24-,25-,26+,28-,29+,30+,31+,35+,36-,37+,38-/m0/s1

Epmedin B - Physico-chemical Properties

Molecular FormulaC38H48O19
Molar Mass808.78
Density1.60±0.1 g/cm3(Predicted)
Melting Point162-164 °C
Boling Point1066.1±65.0 °C(Predicted)
Flash Point325.6°C
Solubility DMSO : 33.33 mg/mL (41.21 mM; Need ultrasonic)
Vapor Presure0mmHg at 25°C
AppearanceYellow powder
pKa5.90±0.40(Predicted)
Storage Condition2-8℃
Refractive Index1.685
MDLMFCD04039834
Physical and Chemical PropertiesYellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Epimedium herb.

Epmedin B - Risk and Safety

HS Code29329990

Epmedin B - Reference

Reference
Show more
1. Wang Ying, Gao Xia, Chen Yan, et al. Effect of carbomer on enzymatic hydrolysis of total flavonoids from epimedium [J]. Chinese Journal of Experimental Formulas 2014 20(009):1-5.
2. Fan Xing, Yang Chengzi, Bao Xiaping, et al. Study on HPLC Fingerprint of Qigu Capsule [J]. Chinese Herbal Medicine, 2014, 045(009):1257-1261.
3. Wang Yingzhe, Jiang Dacheng, Rong Road, Zodiac Jing Lei, Zhang Qiang, Weng Lili. Comparative Analysis of Flavonoids in Epimedium Korea from Northeast China [J]. Journal of Pharmaceutical Analysis 2019 39(11):2034-2040.
4. Liu Cong Yan Gao Xia Chen Yan et al. Feasibility Study on Improving Oral Bioavailability of Total Flavonoids of Epimedium by Bionic Enzymatic Hydrolysis Enteric-coated Capsules [J]. China Journal of Pharmaceutical Industry 2016(9):1158-1164.
5. Li Jing, Wang Yingzhe, Liu Yucui, Jing Zhixian, Yan Li, Guo Junjie, Jiang Dacheng, Xiao Jinglei. Detection and Analysis of Effects of Geographical Environmental Factors on Spatial Distribution of Flavonoids in Epimedium Korea [J]. Chinese Journal of Traditional Chinese Medicine, 2019,44(24):5368-5374.
6. Zhang Yan. Separation and Purification of Epimedium EF5 Flavonoids by Macroporous Adsorption Resin [J]. Northern Pharmacy, 2015, 000(011):11-13.
7. Jiang Xingang, Jia Jiming, Li Yishuang. UPLC Fingerprint of Jinlida Granules [J]. Chinese Journal of Experimental Prescriptions, 2013, 19(001):126-129.
8. Liu congyan, Gao Xia, Huang mengmeng, et al. preparation and evaluation of epimedium total flavonoids biomimetic enzymatic enteric-coated capsules [J]. Chinese herbal medicine, 2016(20).
9. Liu congyan, Gao Xia, Chen Yan, et al. pharmacokinetic behavior of epimedium total flavonoids in osteoporotic rats [J]. Chinese patent medicine, 2017, 39(008):1595-1600.
10. Gao Xia, Liu Xuan, Chen Yan, et al. Biotransformation Process Analysis of Total Flavonoids of Epimedium [J]. Chinese Journal of Traditional Chinese Medicine, 2013, 38(23):4079.
11. Gao Xia, Chen Yan, Wang Ying, et al. Effect of Dextrin Wet Granulation on Enzymatic Hydrolysis of Total Flavonoids of Epimedium [J]. Chinese Medicine, 2014, 36(007):1392-1397.
12. Peng Jing, Ma Yihua, Chen Yan, et al. Simultaneous Biotransformation of Four Flavonoid Glycosides in Epimedium by Immobilized Snail Enzyme [J]. Chinese patent medicine, 2016, 38(9):1984-1990.
13. Yang Chengzi, Fan Xing, Bao Xiaping, et al. Simultaneous Determination of Five Components in Qigu Capsule by HPLC [J]. Chinese Journal of Experimental Prespectology 2015 021(016):60-63.
14. Lan Hai, Liu Xinyan, Yu Ling, Monolan, Zhang Yan, Guo Ziyou, Wu Qing. Purification of epimedium and icariin by macroporous resin [J]. Chinese herbal medicine, 2020,51(17):4473-4481.
15. Xu Ting, Huang Mengmeng, Li Ruiyun, Yang Ru, Liu Lifang, Chen Yan. Study on Quality Evaluation of Different Parts of Multi-base Primary Epimedium [J]. Chinese herbal medicine, 2020,51(01):190-196.
16. Huang Kaidi, Liu Jingxia, Niu Yang, Ma Xueqin, Zhang Ting, Bu Fanshu, Ren Hui, Guo Sheng, Qian Dawei, Duan Jinqi. Study on Quality Control Method of UPLC Fingerprint Combined with Multi-component Content Determination of Huiyao Zhalinusi Fang [J]. Journal of Nanjing University of Traditional Chinese Medicine, 2021,37(01):77-82.
17. Wu Yanyan, Ren Hui Xu, Feng Youlong, Zhang Li, Zhang Yulin. HPLC Fingerprint of Anshen Bunao Capsule and Determination of Three Components [J]. Journal of Guangdong Pharmaceutical University, 2020,36(06):778-783.
18. Zhou, Yan-dan, et al. "Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway." Biomedicine & Pharmacotherapy 109 (2019): 2309-2317.https://doi.org/10.1016/j.biopha. 2018.11.108
19. [IF=4.545] Yan-dan Zhou et al."Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway."Biomed Pharmacother. 2019 Jan;109:2309
20. [IF=4.411] Zhenxian Qin et al."A Widely Metabolomic Analysis Revealed Metabolic Alterations of Epimedium Pubescens Leaves at Different Growth Stages."Molecules. 2020 Jan;25(1):137
21. [IF=3.757] Congyan Liu et al."Enhanced hydrolysis and antitumor efficacy of Epimedium flavonoids mediated by immobilized snailase on silica."Process Biochem. 2019 Nov;86:80
22. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556
Epmedin B
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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Epmedin B Visit Supplier Webpage Request for quotation
CAS: 110623-73-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Epimedin B Visit Supplier Webpage Request for quotation
CAS: 110623-73-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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Epmedin B
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