Name | (3β )-olean-12-ene-3,28-diol |
Synonyms | Aids064685 Aids-064685 ERYTHRODIOL(P) 3Β-ERYTHRODIOL ERYTHRODIOL hplc High root glycol ERYTHRODIOL WITH HPLC Olean-12-ene-3b,28-diol )-olean-12-ene-3,28-diol Erythrodiol,Olean-12-ene-3β,28-diol |
CAS | 545-48-2 |
EINECS | 208-890-4 |
InChI | InChI=1/C30H50O2/c1-25(2)14-16-30(19-31)17-15-28(6)20(21(30)18-25)8-9-23-27(5)12-11-24(32)26(3,4)22(27)10-13-29(23,28)7/h8,21-24,31-32H,9-19H2,1-7H3/t21?,22?,23?,24-,27-,28+,29+,30+/m0/s1 |
Molecular Formula | C30H50O2 |
Molar Mass | 442.72 |
Density | 1.05±0.1 g/cm3(Predicted) |
Melting Point | 230-231°C(lit.) |
Boling Point | 520.5±50.0 °C(Predicted) |
Specific Rotation(α) | 77 |
Flash Point | 209.9°C |
Solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
Vapor Presure | 5.22E-13mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
BRN | 2340203 |
pKa | 15.09±0.10(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Refractive Index | 1.551 |
Risk Codes | 22 - Harmful if swallowed |
Safety Description | S2 - Keep out of the reach of children. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-23 |
overview | Pittosporumtobira(Thunb. Volatile aromatic compounds such as citral, ethyl acetoacetate and butanone alcohol in their branches and leaves have strong air purification functions. Plants can also absorb heavy metal Zn and photochemical smog, which is a good anti-pollution tree species. Its roots can dispel wind and activate collaterals, dispel blood stasis and relieve pain, leaves can detoxify, stop bleeding, seeds can astray intestines, solid essence, etc.; plant extracts have a certain effect on obesity and diabetes. Some studies have further separated the ethyl acetate extract of the ethanol extract of the dried powder of Haitong leaves, and separated high-root glycol (Erythrodiol, also known as coca glycol) from it for the first time, and found that it has high herbicidal activity for the first time. |
biological activity | Erythrodiol is a component of olive oil. Erythrodiol promotes cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol have potential for atherosclerosis research. |
target | ABCA1 protein |
Cell Line: | THP-1 macrophage cells |
Concentration: | 1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM |
Incubation Time: | 24 hours |
Result: | Increased ABCA1 protein expression. |