Escin IVb
isoescin Ib
CAS: 219944-46-4
Molecular Formula: C55H86O24
Escin IVb - Names and Identifiers
Escin IVb - Physico-chemical Properties
| Molecular Formula | C55H86O24 |
| Molar Mass | 1131.26 |
| Density | 1.46 |
| Melting Point | 223.2-225.5°C |
| Boling Point | 1148.1±65.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.1 in MeOH)-4.3 |
| Flash Point | 314.1°C |
| Solubility | Soluble in water and methanol, soluble in ethanol and butanol, insoluble in chloroform and acetic acid. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White powder |
| pKa | 2.63±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.627 |
| MDL | MFCD12031630 |
| In vitro study | β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity. |
Escin IVb - Reference
| Reference Show more | 1. Nie Fang, Lu Weiqi, Tang Shengling. Simultaneous Determination of 4 Aescin [J] in Saluzi from 14 producing areas by HPLC. Chinese patent medicine 2018 40(12):2703-2708. |
Escin IVb - Reference Information
| biological activity | Isoescin IB was isolated from Aesculus chinensis seeds, which is an isomer of Escin IB. Isoescin IB and Escin IB are the main active ingredients in Escin. |
| in vitro study | β-escin is the major active ingredient in horse chestnut seeds extracts. Beta-Escin can inhibit propagation and/or industry apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity. |
Last Update：2024-04-09 02:00:02
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Product Name: Isoescin IB Visit Supplier Webpage Request for quotationCAS: 219944-46-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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