Ethanone, 2-amino-1-(2-chlorophenyl)-
2-Amino-2'-chloroacetophenone
CAS: 743357-99-5
Molecular Formula: C8H8ClNO
Ethanone, 2-amino-1-(2-chlorophenyl)- - Names and Identifiers
| Name | 2-Amino-2'-chloroacetophenone |
| Synonyms | a-Amino-2chloroacetophenone 2-AMINO-2'-CHLOROACETOPHENONE α-Amino-2'-chloroacetophenone 2-Amino-2'-chloroacetophenone 2-Amino-1-(2-chlorophenyl)ethanone 2-Chlorophenacylamine hydrochloride Ethanone, 2-amino-1-(2-chlorophenyl)- ethanone, 2-amino-1-(2-chlorophenyl)- 2-aMino-1-(2-chlorophenyl)ethan-1-one alpha-Amino-2'-chloroacetophenone hydrochloride |
| CAS | 743357-99-5 |
| InChI | InChI=1/C8H8ClNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4H,5,10H2 |
Ethanone, 2-amino-1-(2-chlorophenyl)- - Physico-chemical Properties
| Molecular Formula | C8H8ClNO |
| Molar Mass | 169.61 |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Boling Point | 256.9±20.0 °C(Predicted) |
| Flash Point | 109.2°C |
| Vapor Presure | 0.015mmHg at 25°C |
| pKa | 6.74±0.29(Predicted) |
| Refractive Index | 1.568 |
Ethanone, 2-amino-1-(2-chlorophenyl)- - Introduction
2-Amino-2 '-chloroacetophenone(2-Amino-2'-chloroacetophenone) is an organic compound with the formula C8H8ClNO. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Amino-2 '-chloroacetophenone is a colorless to pale yellow crystalline solid with a special odor. It is stable at room temperature, soluble in organic solvents such as ethanol, acetone and ether, and insoluble in water.
Use:
2-Amino-2 '-chloroacetophenone is often used as an important intermediate in organic synthesis. It can be used to synthesize biologically active compounds, such as compounds with antibacterial and antioxidant activity. In addition, it can also be used in the synthesis of dyes, drugs and organic photosensitizers.
Preparation Method:
The preparation of 2-Amino-2 '-chloroacetophenone is usually carried out by the method of chlorinating acetophenone. The specific steps include reacting acetophenone with chlorine gas in the presence of a catalyst to obtain 2-chloroacetophenone, which is then converted to 2-Amino-2 '-chloroacetophenone by the reaction of aqueous ammonia and acid.
Safety Information:
There is limited information on the toxicity and hazards of 2-Amino-2 '-chloroacetophenone, but as an organic substance, attention should be paid to safe operation. During use, avoid contact with skin, eyes and respiratory tract, and prevent swallowing. In the laboratory environment, relevant safety procedures and personal protective measures should be followed. If ingested or inhaled, seek medical attention immediately.
Nature:
2-Amino-2 '-chloroacetophenone is a colorless to pale yellow crystalline solid with a special odor. It is stable at room temperature, soluble in organic solvents such as ethanol, acetone and ether, and insoluble in water.
Use:
2-Amino-2 '-chloroacetophenone is often used as an important intermediate in organic synthesis. It can be used to synthesize biologically active compounds, such as compounds with antibacterial and antioxidant activity. In addition, it can also be used in the synthesis of dyes, drugs and organic photosensitizers.
Preparation Method:
The preparation of 2-Amino-2 '-chloroacetophenone is usually carried out by the method of chlorinating acetophenone. The specific steps include reacting acetophenone with chlorine gas in the presence of a catalyst to obtain 2-chloroacetophenone, which is then converted to 2-Amino-2 '-chloroacetophenone by the reaction of aqueous ammonia and acid.
Safety Information:
There is limited information on the toxicity and hazards of 2-Amino-2 '-chloroacetophenone, but as an organic substance, attention should be paid to safe operation. During use, avoid contact with skin, eyes and respiratory tract, and prevent swallowing. In the laboratory environment, relevant safety procedures and personal protective measures should be followed. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-09 21:54:55
