Ethyl (R)-1-Boc-nipecotate

Ethyl (R)-1-Boc-nipecotate - Names and Identifiers

Name	(R)-1-Boc-3-Hydroxymethylpiperidine Ethyl Ester
Synonyms	ethyl (r)-1-boc-nipecotate Ethyl (R)-1-Boc-nipecotate Ethyl (R)-N-Boc-piperidine-3-carboxylate (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER (R)-1-Boc-3-Hydroxymethylpiperidine Ethyl Ester 1-tert-butyl 3-ethyl (3R)-piperidine-1,3-dicarboxylate Ethyl (3R)-1-tert-butoxycarbonyl-3-piperidinecarboxylate Ethyl (R)-1-(tert-Butoxycarbonyl)-3-piperidinecarboxylate (R)-1,3-Piperidinedicarboxylic acid 1-tert-butyl 3-ethyl ester 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester,(3R)- 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R)- 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R)- (9CI)
CAS	194726-40-4
InChI	InChI=1/C13H23NO4/c1-5-17-11(15)10-7-6-8-14(9-10)12(16)18-13(2,3)4/h10H,5-9H2,1-4H3/t10-/m1/s1

Ethyl (R)-1-Boc-nipecotate - Physico-chemical Properties

Molecular Formula	C13H23NO4
Molar Mass	257.33
Density	1.077
Melting Point	35.0 to 39.0 °C
Boling Point	323.9°C at 760 mmHg
Flash Point	>110℃
Vapor Presure	0.000254mmHg at 25°C
Appearance	powder to lump to clear liquid
Color	White or Colorless to Almost white or Almost colorless
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.473

Ethyl (R)-1-Boc-nipecotate - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

Ethyl (R)-1-Boc-nipecotate - Introduction

Ethyl Ester is an organic compound with the chemical formula C12H19NO3. It is a colorless liquid with a special smell. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless liquid
-Molecular Weight: 225.29
-Boiling point: About 240 ° C
-Density: About 1.04g/cm³
-Melting point: About -60 ° C
-Solubility: Soluble in many organic solvents, such as alcohol, ether, etc

Use:
(R)-An Ethyl Ester is an organic Ester compound commonly used as an intermediate in synthesis. It has certain applications in the synthesis of drugs and pesticides. Specific uses include synthetic drugs, fragrances, dyes, rubber auxiliaries, etc.

Method:
(R)-Ethyl Ester is commonly prepared by a variety of methods, one of which is to obtain Ethyl piperidinecarboxylate by reacting ethanolamine with piperidinecarboxylic acid, it is then reacted with tert-butyl chlorocarbonate to produce the target product.

Safety Information:
(R)-Ethyl Ester is an organic compound and proper safety measures should be taken. Contact with the skin or inhalation of high concentrations of steam may cause irritation, so direct contact should be avoided during operation to ensure good ventilation. At the same time, the correct storage and handling of chemicals should be followed. When using the compound, it is best to wear appropriate personal protective equipment, such as laboratory gloves and protective glasses. Local laws and regulations should be followed when disposing of waste from this compound.

Last Update：2024-04-09 21:32:38