Ethyl 3-bromo-2-nitrobenzoate - Names and Identifiers
Ethyl 3-bromo-2-nitrobenzoate - Physico-chemical Properties
Molecular Formula | C9H8BrNO4
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Molar Mass | 274.06812 |
Ethyl 3-bromo-2-nitrobenzoate - Introduction
Ethyl 3-bromo-2-nitrobenzoate is an organic compound with the chemical formula C9H8BrNO4. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 3-bromo-2-nitrobenzoic acid ethyl ester is a white or slightly yellow crystalline solid.
2. melting point: its melting point is about 80-84 degrees Celsius.
3. Solubility: It is soluble in some organic solvents, such as alcohol, ether and ethyl acetate.
Use:
3-Bromo-2-nitrobenzoic acid ethyl ester can be used as an intermediate or reagent in organic synthesis for the synthesis of other compounds. It has certain applications in drug synthesis, pesticide synthesis and dye synthesis.
Preparation Method:
The preparation of 3-bromo-2-nitrobenzoic acid ethyl ester can be carried out by the following steps:
1.3-bromo -2-nitrobenzoic acid reacts with hydrochloric acid to generate 3-bromo -2-nitrobenzoate.
2.3-bromo -2-nitrobenzoate is reacted with alkali to generate the corresponding sodium salt.
3. Finally, the sodium salt is reacted with ethanol to generate ethyl 3-bromo-2-nitrobenzoate.
Precautions and Safety Information:
1. 3-Bromo-2-nitrobenzoic acid ethyl ester is an organic compound and should be used in a well-ventilated place and avoid inhaling its vapor or dust.
2. during operation, should wear appropriate personal protective equipment, such as gloves, protective glasses and laboratory coat.
3. avoid contact with the skin, such as contact with the skin, should immediately rinse with plenty of water.
4. in the use or storage process, should avoid contact with oxidants or flammable substances, to prevent dangerous reaction.
5. Ethyl 3-bromo-2-nitrobenzoate is a toxic compound and should be kept away from children and animals.
6. Any operation using this compound should be carried out under suitable laboratory conditions and follow relevant safe operating procedures.
Last Update:2024-04-09 21:00:56