Ethyl 4-amino-2-chloro-5-pyrimidinecarboxylate
Ethyl 4-amino-2-chloropyrimidine-5-carboxylate
CAS: 71406-78-5
Molecular Formula: C7H8ClN3O2
Ethyl 4-amino-2-chloro-5-pyrimidinecarboxylate - Names and Identifiers
Ethyl 4-amino-2-chloro-5-pyrimidinecarboxylate - Physico-chemical Properties
| Molecular Formula | C7H8ClN3O2 |
| Molar Mass | 201.61 |
| Density | 1.395 |
| Melting Point | 156℃ |
| Boling Point | 377℃ |
| Flash Point | 182℃ |
| pKa | 0.55±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Irritant |
| MDL | MFCD09860847 |
Ethyl 4-amino-2-chloro-5-pyrimidinecarboxylate - Introduction
Ethyl, chemical formula for C8H8ClN3O2, is an organic compound.
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 132-134 degrees Celsius
-Solubility: Soluble in many organic solvents such as chloroform, dimethyl ketone and methanol
Use:
- Ethyl is an important intermediate compound that can be used to synthesize biologically active compounds and drugs.
-It can be used to synthesize anticancer drugs, anti-tuberculosis drugs, etc.
Preparation Method:
Ethyl can be prepared by the following steps:
1. Dissolve ethyl chloroformate in dimethyl ketone.
2. Add ammonia and react at low temperature.
3. Add 2-chloropyrimidine and continue the reaction at an appropriate temperature.
4. The product was filtered, crystallized, and then purified.
Safety Information:
- Ethyl is generally stable and safe under normal use and storage conditions.
-But as a chemical substance, it may have certain toxicity and irritation to the human body.
-During use, you must follow the safe operation procedures of the chemical laboratory, wear protective gloves and glasses, and ensure that you operate in a well-ventilated area.
-If you have unintended contact with skin or eyes, rinse immediately with water and seek medical help.
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 132-134 degrees Celsius
-Solubility: Soluble in many organic solvents such as chloroform, dimethyl ketone and methanol
Use:
- Ethyl is an important intermediate compound that can be used to synthesize biologically active compounds and drugs.
-It can be used to synthesize anticancer drugs, anti-tuberculosis drugs, etc.
Preparation Method:
Ethyl can be prepared by the following steps:
1. Dissolve ethyl chloroformate in dimethyl ketone.
2. Add ammonia and react at low temperature.
3. Add 2-chloropyrimidine and continue the reaction at an appropriate temperature.
4. The product was filtered, crystallized, and then purified.
Safety Information:
- Ethyl is generally stable and safe under normal use and storage conditions.
-But as a chemical substance, it may have certain toxicity and irritation to the human body.
-During use, you must follow the safe operation procedures of the chemical laboratory, wear protective gloves and glasses, and ensure that you operate in a well-ventilated area.
-If you have unintended contact with skin or eyes, rinse immediately with water and seek medical help.
Last Update：2024-04-09 15:18:08
