Ethyl 5-bromo-1H-1,2,4-trazole-3-carboxylate
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate
CAS: 774608-89-8
Molecular Formula: C5H6BrN3O2
Ethyl 5-bromo-1H-1,2,4-trazole-3-carboxylate - Names and Identifiers
Ethyl 5-bromo-1H-1,2,4-trazole-3-carboxylate - Physico-chemical Properties
| Molecular Formula | C5H6BrN3O2 |
| Molar Mass | 220.02 |
| Density | 1.763±0.06 g/cm3(Predicted) |
| Boling Point | 354.0±25.0 °C(Predicted) |
| pKa | 5.62±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD11040185 |
Ethyl 5-bromo-1H-1,2,4-trazole-3-carboxylate - Introduction
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate is a chemical substance whose chemical formula is C6H6BrN3O2. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
1. Appearance: Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate is a colorless to slightly yellow solid.
2. melting point: roughly between 80°C-85°C.
3. Solubility: It is easy to dissolve in common organic solvents such as ethanol and chloroform, but it is less soluble in water.
Use:
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate has certain application value in the field of chemistry.
1. It is a commonly used intermediate that can be used to synthesize other compounds, such as organic synthesis reactions in the pharmaceutical field.
2. Due to its specific structure, it can also be used as a precursor for antibacterial drugs and other biologically active compounds.
Preparation Method:
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate can be prepared by the following steps:
1.5-bromo -1H-1,2,4-triazole is reacted with chlorinated carbon to generate 5-bromo -1H-1,2,4-triazole -3-carboxylic acid.
2.5-Bromo-1H-1, 2,4-triazole-3-carboxylic acid reacts with ethanol and an acid catalyst to produce Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate.
Safety Information:
1. Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate should be considered a hazardous chemical. When using must follow the relevant safety measures.
2. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, flush immediately with plenty of water and seek medical help.
3. During use, proper ventilation is very important to avoid inhaling its vapors.
4. In the storage and disposal, should follow the relevant safety regulations and environmental protection regulations.
Nature:
1. Appearance: Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate is a colorless to slightly yellow solid.
2. melting point: roughly between 80°C-85°C.
3. Solubility: It is easy to dissolve in common organic solvents such as ethanol and chloroform, but it is less soluble in water.
Use:
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate has certain application value in the field of chemistry.
1. It is a commonly used intermediate that can be used to synthesize other compounds, such as organic synthesis reactions in the pharmaceutical field.
2. Due to its specific structure, it can also be used as a precursor for antibacterial drugs and other biologically active compounds.
Preparation Method:
Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate can be prepared by the following steps:
1.5-bromo -1H-1,2,4-triazole is reacted with chlorinated carbon to generate 5-bromo -1H-1,2,4-triazole -3-carboxylic acid.
2.5-Bromo-1H-1, 2,4-triazole-3-carboxylic acid reacts with ethanol and an acid catalyst to produce Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate.
Safety Information:
1. Ethyl 5-bromo-1H-1,2,4-triazole-3-carboxylate should be considered a hazardous chemical. When using must follow the relevant safety measures.
2. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, flush immediately with plenty of water and seek medical help.
3. During use, proper ventilation is very important to avoid inhaling its vapors.
4. In the storage and disposal, should follow the relevant safety regulations and environmental protection regulations.
Last Update：2024-04-09 15:18:08
