Ethyl 5-nitrobenzofuran-2-carboxylate - Names and Identifiers
Ethyl 5-nitrobenzofuran-2-carboxylate - Physico-chemical Properties
Molecular Formula | C11H9NO5
|
Molar Mass | 235.19 |
Density | 1.362 |
Melting Point | 152-156 °C |
Boling Point | 377.58°C (rough estimate) |
Flash Point | 171.3°C |
Vapor Presure | 2.34E-05mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.4950 (estimate) |
Ethyl 5-nitrobenzofuran-2-carboxylate - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29329990 |
Hazard Class | IRRITANT |
Ethyl 5-nitrobenzofuran-2-carboxylate - Introduction
Ethyl, also known as Ethyl, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Ethyl is a yellow crystal or powder.
-Chemical formula: C12H9NO5
-Molecular weight: 239.20g/mol
-Melting point: 68-72 degrees Celsius
-Boiling point: 329 degrees Celsius
Use:
Ethyl can be used as an intermediate in organic synthesis, and is often used in drug synthesis and pesticide synthesis.
Preparation Method:
Ethyl's preparation can be carried out through the following steps:
1. Dissolve 5-nitrobenzofuran-2-carboxylic acid and anhydrous ethanol (ethyl alcohol) in dimethylformamide (DMF).
2. Add thionyl chloride (thionyl chloride) as a reactant to maintain the reaction chamber at an appropriate temperature.
3. After the reaction, the target product is extracted by adding cold water and an extractant (such as acetone).
4. Finally, the product is purified by crystallization or distillation.
Safety Information:
Ethyl is an organic compound, and the following safety precautions need to be paid attention:
-The compound may be toxic to the human body, and direct contact or inhalation should be avoided. Wear appropriate personal protective equipment when using.
-During preparation or operation, care should be taken to prevent dust or vapor, and avoid contact with eyes, skin or ingestion into the body.
-Avoid direct sunlight and high temperature during storage. It should be kept in a dry, cool, well-ventilated place, and away from flammable and combustible materials.
-When handling the compound, it should be operated in accordance with relevant safety procedures and protective measures, and comply with local safety regulations. Cheap items cannot be contacted with them to avoid accidental reactions or accidents.
Please note that when carrying out chemical synthesis or operation, you should have relevant chemical experiment skills and laboratory safety knowledge, and strictly abide by relevant safety operation procedures.
Last Update:2024-04-09 19:05:51