FMOC PROTECTED (S)-B-(P-FLUOROPHENYL)-B-ALANINE

FMOC PROTECTED (S)-B-(P-FLUOROPHENYL)-B-ALANINE - Names and Identifiers

Name	Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid
Synonyms	RARECHEM LK FC T330 FMOC-BETA-PHE(4-F)-OH FMOC-D-PHG(4-F)-(C*CH2)OH Fmoc-beta-(S)-4-fluorophenylalanine FMOC-(S)-4-FLUORO-BETA-PHENYLALANINE FMOC PROTECTED (S)-B-(P-FLUOROPHENYL)-B-ALANINE Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid FMOC-(S)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID FMOC-(S)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPANOIC ACID
CAS	479064-89-6

FMOC PROTECTED (S)-B-(P-FLUOROPHENYL)-B-ALANINE - Physico-chemical Properties

Molecular Formula	C24H20FNO4
Molar Mass	405.42
Storage Condition	2-8°C

FMOC PROTECTED (S)-B-(P-FLUOROPHENYL)-B-ALANINE - Introduction

Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid(Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid) is an organic compound. Here is some information about the compound:

Nature:
-Appearance: Typically a white to off-white crystalline solid.
-Molecular formula: C22H18FNO3S
-Molecular weight: 397.45g/mol
-melting point: about 140-145 ℃
-Solubility: Good solubility in organic solvents (such as dimethyl sulfoxide, dimethylformamide and chloroform).

Use:
Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid is commonly used in peptide synthesis in organic synthesis. It is a commonly used amino acid derivative that can be used to synthesize polypeptides with specific structures and functions.

Preparation Method:
The preparation of Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid can be carried out by the following steps:
1. First, benzyl alcohol is reacted with tetrafluoroboric acid to obtain the corresponding aryl borate ester.
2. Then, the aryl borate ester is reacted with the corresponding halogenated acetone in the presence of a base catalyst to generate an aryl-acetone derivative.
3. Finally, the aryl-acetone derivative is reacted with an appropriate amine compound to introduce an amino group to prepare Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-propionic acid.

Safety Information:
Fmoc-S-3-Amino-3-(4-fluoro-phenyl)-The specific safety information of the propionic acid needs to be determined according to the environment and experimental conditions in which it is located. The compound may be irritating to the eyes, skin and respiratory system, so personal protection and appropriate laboratory procedures should be used. When used in a laboratory environment, relevant safety practices should be followed and appropriate protective measures (such as gloves, loose lab clothes and protective glasses) should be provided to ensure the safety of personnel.

Last Update：2024-04-10 22:29:15