Name | FUMONISIN B2 |
Synonyms | FB2 FUMONISIN B3 FUMONISIN B2 FUMONISIN B2, FUSARIUM MONILIFORME yl)-2-(1-methylpentyl)-1,2-ethanediyl)ester 1,2,3-propanetricarboxylicacid,1,1'-(1-(2-amino-9,11-dihydroxy-2-methyltridec 1,2,3-propanetricarboxylicacid,1,1'-(1-(2-amino-9,11-dihydroxy-2-methyltridec 2,2'-{(19-amino-16,18-dihydroxy-5,9-dimethylicosane-6,7-diyl)bis[oxy(2-oxoethane-2,1-diyl)]}dibutanedioic acid 1,2,3-PROPANETRICARBOXYLIC ACID, 1,1'-[1-(12-AMINO-9,11-DIHYDROXY-2-METHYL-TRIDECYL)-2-(1-METHYLPENTYL)-1,2-ETHANE-DIYL]ESTER 1,2,3-PROPANETRICARBOXYLIC ACID, 1,1'-[1-(12-AMINO-4,11-DIHYDROXY-2-METHYL-TRIDECYL)-2-(1-METHYLPENTYL)-1,2-ETHANE-DIYL]ESTER (2R,2'R)-2,2'-{[(5R,6R,7S,9S,16R,18S,19S)-19-amino-16,18-dihydroxy-5,9-dimethylicosane-6,7-diyl]bis[oxy(2-oxoethane-2,1-diyl)]}dibutanedioic acid |
CAS | 116355-84-1 |
EINECS | 601-424-4 |
InChI | InChI=1/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)/t20-,21+,22-,23+,24+,25+,26-,27-,32+/m0/s1 |
Molecular Formula | C34H59NO14 |
Molar Mass | 705.83 |
Density | 1.2044 (rough estimate) |
Boling Point | 705.92°C (rough estimate) |
Flash Point | 6°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 7.57E-35mmHg at 25°C |
Appearance | Off-white solid |
Color | Off-White to Beige |
pKa | 3?+-.0.23(Predicted) |
Storage Condition | -20°C |
Stability | Hygroscopic |
Refractive Index | 1.6630 (estimate) |
Physical and Chemical Properties | Storage Conditions:? 20℃ WGK Germany:3 RTECS:TZ8335000 |
Risk Codes | R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 2811 6.1/PG 1 |
WGK Germany | 3 |
RTECS | TZ8335000 |
HS Code | 29221990 |
introduction | fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is an effective sphingosine N-acyltransferase (ceramide synthase) inhibitor that blocks the de novo synthesis of sphingolipids. |
harmfulness | fumonisin B2 is a mycotoxin produced by Fusarium moniliforme in various grains. it is an effective inhibitor of sphingosine N-acyltransferase(ceramide synthase) to block the de novo synthesis of sphingolipids. Fumisin (FB) is a mycotoxin, which is a structurally similar diester compound composed of different polyhydroalcohols and maletricarboxylic acids. Among them, Fumisin B1(FB1), Fumisin B2(FB2) and Fumisin B3(FB3) are the main components of contaminated food and its products, and are also potential factors that induce cancer, the International Agency for Research on Cancer has declared fumonisin a "2B" grade poison (a possible carcinogen for humans). |
biological activity | Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is an effective sphingosine N-acyltransferase (ceramide synthase) inhibitor that blocks the de novo synthesis of sphingolipids. |
target | Sphingosine N-acyltransferase |
category | toxic substances |
toxicity classification | highly toxic |
acute toxicity | oral-monkey TDL0: 10 mg/kg |
flammability hazard characteristics | combustible, spicy and irritating smoke from the fire site |
storage and transportation characteristics | warehouse is low temperature, ventilated and dry; Store separately from food raw materials |
fire extinguishing agent | water, carbon dioxide, dry powder, sand |