Molecular Formula | C30H41NO10 |
Molar Mass | 575.65 |
Density | 1.202±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 734.8±60.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Oil |
Color | Colourless |
pKa | 4.28±0.10(Predicted) |
Storage Condition | 2-8°C |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
HS Code | 29225090 |
biological activity | Fmoc-NH-PEG6-CH2CH2COOH is a degradable ADC linker used in antibody drug conjugate (ADC) synthesis. |