Formamide, N-(4-bromophenyl)-
N-4-(溴苯基)甲酰胺
CAS: 2617-78-9
Molecular Formula: C7H6BrNO
Formamide, N-(4-bromophenyl)- - Names and Identifiers
Formamide, N-(4-bromophenyl)- - Physico-chemical Properties
| Molecular Formula | C7H6BrNO |
| Molar Mass | 200.03 |
| Density | 1.634±0.06 g/cm3(Predicted) |
| Melting Point | 117-121°C(lit.) |
| Boling Point | 334.3±25.0 °C(Predicted) |
| pKa | 14.13±0.70(Predicted) |
Formamide, N-(4-bromophenyl)- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| RTECS | LQ4663000 |
Formamide, N-(4-bromophenyl)- - Introduction
N-4-(Bromophenyl) formamide is an organic compound whose chemical formula is C8H7BrNO. It is a white solid that is stable at room temperature. The following is a description of the properties, uses, preparation and safety information of N-4-(bromophenyl) formamide:
Nature:
1. Appearance: white solid
2. molecular weight: 216.05g/mol
3. Melting point: 110-113°C
4. Solubility: slightly soluble in water, soluble in organic solvents such as ethanol, ether, etc.
Use:
N-4-(Bromophenyl) formamide has a variety of uses in the chemical and pharmaceutical fields, such:
1. for organic synthesis: can be used as an important intermediate, participate in the synthesis of other organic compounds
2. Heterocyclic compounds as bromine-containing functional groups: commonly used in drug development and pesticide manufacturing
3. for the synthesis of anti-tumor drugs: has a certain anti-tumor activity, can be used as a precursor of related drugs
Preparation Method:
The preparation method of N-4-(bromophenyl) formamide is as follows:
The reaction of bromobenzene and formamide in an appropriate solvent usually requires the addition of a catalyst, such as zinc chloride or copper iodide. The reaction is usually carried out at room temperature, and after the end of the reaction the solution is treated with water and then the product is extracted.
Safety Information:
The safe operation of N-4-(bromophenyl) formamide requires attention to the following:
1. Irritating to skin and eyes, rinse with water immediately after contact.
2. Because N-4-(bromophenyl) formamide is an organic bromine compound, it may cause harm to the environment and requires proper disposal and disposal of waste.
3. during storage and use, it is necessary to avoid contact with oxidants, strong acids, strong bases and other substances to avoid dangerous reactions.
Nature:
1. Appearance: white solid
2. molecular weight: 216.05g/mol
3. Melting point: 110-113°C
4. Solubility: slightly soluble in water, soluble in organic solvents such as ethanol, ether, etc.
Use:
N-4-(Bromophenyl) formamide has a variety of uses in the chemical and pharmaceutical fields, such:
1. for organic synthesis: can be used as an important intermediate, participate in the synthesis of other organic compounds
2. Heterocyclic compounds as bromine-containing functional groups: commonly used in drug development and pesticide manufacturing
3. for the synthesis of anti-tumor drugs: has a certain anti-tumor activity, can be used as a precursor of related drugs
Preparation Method:
The preparation method of N-4-(bromophenyl) formamide is as follows:
The reaction of bromobenzene and formamide in an appropriate solvent usually requires the addition of a catalyst, such as zinc chloride or copper iodide. The reaction is usually carried out at room temperature, and after the end of the reaction the solution is treated with water and then the product is extracted.
Safety Information:
The safe operation of N-4-(bromophenyl) formamide requires attention to the following:
1. Irritating to skin and eyes, rinse with water immediately after contact.
2. Because N-4-(bromophenyl) formamide is an organic bromine compound, it may cause harm to the environment and requires proper disposal and disposal of waste.
3. during storage and use, it is necessary to avoid contact with oxidants, strong acids, strong bases and other substances to avoid dangerous reactions.
Last Update：2024-04-09 19:06:00
