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GINSENOSIDE F4 (GF4)

Ginsenoside F4

CAS: 181225-33-2

Molecular Formula: C42H70O12

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GINSENOSIDE F4 (GF4) - Names and Identifiers

Name Ginsenoside F4
Synonyms Ginsenoside F4
ginsenoside F4
GINSENOSIDE F4 (GF4)
Ginsenoside F4 (20E)
(20E)-Ginsenoside F4
Δ20(22)-Ginsenoside Rg6
Ginsenoside Rg6 (incorr
β-D-Glucopyranoside, (3β,6α,12β,20E)-3,12-dihydroxydammara-20(22),24-dien-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
CAS 181225-33-2

GINSENOSIDE F4 (GF4) - Physico-chemical Properties

Molecular FormulaC42H70O12
Molar Mass767.01
Density1.28±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point177-181°C
Boling Point851.6±65.0 °C(Predicted)
Specific Rotation(α)(c, 0.28 in MeOH)-7.93
Solubility Soluble in pyridine, DMSO, methanol
AppearanceWhite powder
pKa12.85±0.70(Predicted)
Storage Condition2-8℃
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginseng.

GINSENOSIDE F4 (GF4) - Reference

Reference
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1. Qin, Z., Jia, M., Yang, J. et al. Multiple circulating alkaloids and saponins from intravenous Kang-Ai injection inhibit human cytochrome P450 and UDP-glucuronosyltransferase isozymes: potential drug–drug interactions. Chin Med 15, 69 (2020). https://doi.o
2. [IF=5.34] Shan-Shan Zhou et al."Stronger anti-obesity effect of white ginseng over red ginseng and the potential mechanisms involving chemically structural/compositional specificity to gut microbiota."Phytomedicine. 2020 Aug;74:152761
3. [IF=3.935] Shan-Shan Zhou et al."Synchronous characterization of carbohydrates and ginsenosides yields deeper insights into the processing chemistry of ginseng."J Pharmaceut Biomed. 2017 Oct;145:59
4. [IF=3.645] Mengmeng Jia et al."UHPLC coupled with mass spectrometry and chemometric analysis of Kang-Ai injection based on the chemical characterization, simultaneous quantification, and relative quantification of 47 herbal alkaloids and saponins."J Sep Sci. 2020 Ju
5. [IF=3.105] Zhao Yan et al.Protopanaxadiol and Protopanaxatriol Ginsenosides Can Protect Against Aconitine-induced Injury in H9c2 Cells by Maintaining Calcium Homeostasis and Activating the AKT Pathway.J Cardiovasc Pharm. 2021 Nov;78(5):e690-e702
6. [IF=2.419] Yinping Jin et al."Dynamic changes of ginsenosides in Panax quinquefolius fruit at different development stages measured by UHPLC-Orbitrap MS."Rapid Communications In Mass Spectrometry. 2022 Feb 17
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GINSENOSIDE F4 (GF4)
(2E)-2-(乙氧基亚甲基)-3-氧代-戊酸乙酯
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