Molecular Formula | C22H24ClFN4O4 |
Molar Mass | 462.9 |
Storage Condition | 2-8°C,密封,干燥 |
biological activity | Gefitinib N-oxide is a N-oxide derivative of Gefitinib. Gefitinib is a potent (EGFR) inhibitor with IC50 values of 2-37 nM in nr6wt EGFR cells. |
Target | IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells) |