Molecular Formula | C53H86O22 |
Molar Mass | 1075.24 |
Density | 1.46 |
Melting Point | 235-236°C |
Specific Rotation(α) | (c, 3.4 in Py)-8.2;(c, 2.4 in EtOH)+12.5 |
Solubility | Soluble in methanol and ethanol |
Appearance | grayish yellow crystal |
pKa | 12.50±0.70(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Easily absorbing moisture |
MDL | MFCD03424249 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol and ethanol, derived from honeysuckle. |
In vivo study | A liquid chromatography-electrospray ionization-mass spectrometry method has been developed and validated for identification and quantification of four major bioactive saponins in rat plasma after oral administration of extraction of saponins from Flos Lonicerae, i.e., Macranthoidin B, Macranthoidin A, Dipsacoside B, and Macranthoside B. The retention time of Macranthoidin B, Macranthoidin A, Dipsacoside B, Macranthoside B and IS are 10.65, 12.11, 13.81, 23.31 and 5.47 min, respectively. Taking Macranthoidins A, B, Dipsacoside B (saponins), sweroside (iridoids), and luteolin-7-O-d-glucoside (flavonoids) as markers, a method of ultra high performance liquid chromatography with triple quadrupole mass spectrometry is employed to determine their amounts in Lonicerae Flos, Lonicerae Japonicae Flos, and Lonicerae Japonicae Flos preparations. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29389090 |
Reference Show more | 1. Wang Hongjin, Wang Hongyu, he ran, Wu Junjie, Xu Xiaoyu. Study on hemolysis of flower bud extract of Lonicera macranthoides and its two main saponins [J]. Chinese pharmacological Bulletin, 2016,32(01):43-48. 2. Gao Shan, Guo Yuechu, Liu slang. Comparative identification analysis of present honeysuckle and Lonicera japonica [J]. Chinese medical science,, 007(001):52-55,154. 3. [IF = 3.882] kupeng Yin et al."Lanthanide Metal-Organic Framework-Based fluorecent Sensor Arrays to discover and Quantify medicines of Natural Medicine. Langmuir. 2021;37(17):5321-5328 |