HC≡C-CH2-PEG4-SH
Propargyl-PEG4-thiol
CAS: 1347750-80-4
Molecular Formula: C11H20O4S
HC≡C-CH2-PEG4-SH - Names and Identifiers
| Name | Propargyl-PEG4-thiol |
| Synonyms | SH-PEG4-ALKYNE HC≡C-CH2-PEG4-SH ALKYNE-PEG4-THIOL Propyne-PEG4-thiol Propargyl-PEG4-thiol 3,6,9,12-Tetraoxapentadec-14-yne-1-thiol |
| CAS | 1347750-80-4 |
HC≡C-CH2-PEG4-SH - Physico-chemical Properties
| Molecular Formula | C11H20O4S |
| Molar Mass | 248.3391 |
| Storage Condition | 2-8°C，惰性气体保存 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
HC≡C-CH2-PEG4-SH - Reference Information
| biological activity | Propargyl-PEG4-thiol is a PROTAC Bridge belonging to the PEG class. Propargyl-PEG4-thiol can be used to synthesize a range of PROTAC molecules. Propargyl-PEG4-thiol is a non-cleavable ADC Bridge for the synthesis of antibody drug conjugates (ADCs). |
Last Update：2024-04-09 21:54:55
