HPLClabelingreagentfore.e.determination

HPLClabelingreagentfore.e.determination - Names and Identifiers

Name	(S)-(+)-4-NITRO-7-(3-AMINOPYRROLIDIN-1-YL)-2,1,3-BENZOXADIAZOLE
Synonyms	(S)-NBD-APY (S)-(+)-NBD-APY HPLClabelingreagentfore.e.determination (S)-(+)-4-NITRO-7-(3-AMINOPYRROLIDIN-1-YL)BENZOFURAZAN 3S-(4-(3-AMINOPYRROLIDIN-1-YL))-7-NITROBENZ-2-OXA-1,3-DIAZOLE (S)-(+)-4-NITRO-7-(3-AMINOPYRROLIDIN-1-YL)-2,1,3-BENZOXADIAZOLE
CAS	143112-52-1
InChI	InChI=1/C10H11N5O3/c11-6-3-4-14(5-6)7-1-2-8(15(16)17)10-9(7)12-18-13-10/h1-2,6H,3-5,11H2/t6-/m0/s1

HPLClabelingreagentfore.e.determination - Physico-chemical Properties

Molecular Formula	C10H11N5O3
Molar Mass	249.23
Melting Point	178-184°C
Appearance	powder to crystal
Color	Light yellow to Amber to Dark green
Storage Condition	2-8°C
Refractive Index	14.5 ° (C=0.2, CH3CN
Physical and Chemical Properties	Storage Conditions: 2-8 ℃

HPLClabelingreagentfore.e.determination - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

HPLClabelingreagentfore.e.determination - Introduction

Nitroaminopyrrolidine benzoxazine, also known as N-nitro-N'-aminopyrrolidine benzoxazine, has the chemical formula C11H9N5O2. The following describes its nature, use, preparation and safety information:

Nature:
Nitroaminopyrrolidine benzoxazine is a yellow crystal with a relative molecular mass of 251.22. It has strong toxicity, high ignition point, slightly soluble in water, soluble in organic solvents.

Use:
Nitroaminopyrrolidine benzoxazine is an important raw material in organic synthesis. It is mainly used to synthesize some compounds with biological activity, such as nitrogen-containing pesticides, chemiluminescence materials, pharmaceutical intermediates, etc.

Preparation Method:
Nitroaminopyrrolidine benzoxazine can be prepared by a variety of methods, one of the commonly used methods is to react pyrrolidine with nitric acid to obtain nitropyrrolidine, and then undergo a substitution reaction to obtain the target product. In the preparation process, it is necessary to control the reaction conditions to improve the yield and selectivity.

Safety Information:
Nitroaminopyrrolidine benzoxazine has high toxicity and may cause harm to humans and the environment. During storage and use, care should be taken to prevent it from contacting with oxidants, strong acids, strong bases and other substances to avoid unsafe chemical reactions. At the same time, appropriate protective measures should be taken, such as wearing protective gloves, goggles, etc., to ensure the safety of staff.

Last Update：2024-04-09 21:11:58