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Hydroxylapatite, Fast Flow

hydroxylapatite

CAS: 1306-06-5

Molecular Formula: Ca5HO13P3

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Hydroxylapatite, Fast Flow - Names and Identifiers

Name hydroxylapatite
Synonyms Durapatite
Apatite HAP
Hydroxyapatite
hydroxylapatite
apatite,hydroxy
hydroxyapatite type I
Hydroxylapatite, Fast Flow
Calcium phosphate hydroxide
hydroxylapatite high resolution
CALCIUM PHOSPHATE, HYDROXIDE REAGENT
CALCIUM PHOSPHATE, HYDROXIDE PURIFIED
Calcium phosphate hydroxide, Durapatite, Hydroxylapatite
Hydroxyapatite,Calcium hydroxyphosphate, Calcium phosphate tribasic, HAp, Hydroxylapatite
CAS 1306-06-5
EINECS 215-145-7
InChI InChI=1/5Ca.H3O4P.H2O/c;;;;;1-5(2,3)4;/h;;;;;(H3,1,2,3,4);1H2/q5*+2;;/p-4

Hydroxylapatite, Fast Flow - Physico-chemical Properties

Molecular FormulaCa5HO13P3
Molar Mass502.31
Density3.076 g/cm3(Temp: 18 °C)
Melting Point1100°C(lit.)
Boling Point158℃ at 760 mmHg
Water Solubilityinsoluble H2O [MER06]
Solubility H2O: 0.3mg/mL, clear, colorless
AppearanceWhite crystal
ColorWhite
Merck13,3500
Storage Condition2-8°C
MDLMFCD00010904
Physical and Chemical PropertiesHydroxyapatite has high specific surface area, strong water absorption and water release ability and moisture absorption ability in air. The density of hydroxyapatite is 3.16g/cm3, the specific surface area is 26 m2/g, the solubility product constant Ksp(25 ℃)=(6.3±2.1)× 10-59, which is weakly alkaline (pH = 7-9), insoluble in alkali soluble in acid. Hydroxyapatite crystal belongs to the hexagonal structure, which belongs to the P63/m space group, the unit cell parameters a = B = 0.943nm,c = 0.688nm.
UseThis product is for scientific research only and shall not be used for other purposes.

Hydroxylapatite, Fast Flow - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany3
RTECSMY8434000
FLUKA BRAND F CODES3-10
TSCAYes
HS Code28352600

Hydroxylapatite, Fast Flow - Reference

Reference
Show more
1. Guo Yanwei, Li Songfang Dianji. Experimental Study on Repair of Mandibular Defects by BMSCs/PRF Composite Osthole-loaded Scaffold Material in Rabbits [J]. Stomatology Research 2012 28(011):1087-1091.
2. Zhu Quanjie. Effect and Mechanism of HA Nanocarrier Transferred hGM-CSF HepG2 Vaccine on EMT Induced by IL-6 in HepG2 Cells [D]. Hunan Normal University 2017.
3. Lu Bo Wen Yi Zhuang Cheng Wu Yanguang et al. Enhanced Modification of Metakaolin-Fly Ash Base Polymer by Several Fillers [J]. Journal of Wuhan University of Engineering 2020(3):293-297.
4. Gao Hong, Anna, Liu Ping. Analysis of Hypoglycemic Effect of New Oral Administration of Insulin [J]. Chinese Disabled Medicine, 2014, 000(006):156-157.
5. Guo Lingyu, Liu Kai, Liu Shufa. Repair of mandibular defects with concentrated red bone marrow/platelet-rich fibrin combined with autologous periosteal fragments [J]. China Tissue Engineering Research, 17(21).
6. Fang Dianji, Guo Yanwei, Li Song, such as. Experimental Study on Repair of Mandibular Defect in Rabbits with Adipose Stem Cells Combined with Eucommia Alcohol Extract Scaffold Material [J]. West China Journal of Stomatology, 2013, Volume 31, Issue 1, pp. 65-69, MEDLINE ISTIC PKU CSCD, 2013.
7. Deng Biquan, Teng Yu, Hu Hua, Li Jian, Jiang Honghui, Zhang Weiguo. Initial stability of silk fibroin/nano-hydroxyapatite composite after lumbar interbody implantation [J]. China Tissue Engineering Research, 2017,21(26):4160-4166.
8. Gao Zhichao, Li Shanchang, Jin Shandan, et al. Study on bone marrow mesenchymal stem cells combined with isopsoralen-loaded scaffold material to repair bone defects [J]. Stomatology Research, 2012(12):29-33.
9. Geven, Mike A., et al. "Micro-porous composite scaffolds of photo-crosslinked poly (trimethylene carbonate) and nano-hydroxyapatite prepared by low-temperature extrusion-based additive manufacturing." Polymers for advanced technologies 28.10 (2017): 1226-1
10. Cao, Jinxing, Ruizhe Lian, and Xiaohong Jiang. "Magnesium and fluoride doped hydroxyapatite coatings grow by pulsed laser deposition for promoting titanium implant cytocompatibility." Applied Surface Science 515 (2020): 146069.https://doi.org/10.1016/j.ap
11. Cao, Jinxing, et al. "Formation of Porous apatite layer after immersion in SBF of fluorine-hydroxyapatite coatings by pulsed laser deposition improved in vitro cell proliferation." ACS Applied Bio Materials 3.6 (2020): 3698-3706.https://doi.org/10.1021/acs
12. Jiang, Guangpeng, et al. "Characterization of luminescent hydroxyapatite @ terbium complex core-shell composites using chlorobenzoic acid as ligands." Journal of Rare Earths 38.11 (2020): 1165-1170.https://doi.org/10.1016/j.jre. 2019.10.009
13. Zhipeng Wang, Hong Jiang, Xujiao Chen, Xinhua Song, Fengjing Xu, Fangchao Chen, Zhiguo Mao, Shouhong Gao, Wansheng Chen,A rapid and sensitive method for simultaneous determination of eight protein-bound uremic toxins in human serum by UHPLC-MS/MS: applica
14. [IF=6.707] Jinxing Cao et al."Magnesium and fluoride doped hydroxyapatite coatings grown by pulsed laser deposition for promoting titanium implant cytocompatibility."Appl Surf Sci. 2020 Jun;515:146069
15. [IF=6.707] Jinxing Cao et al."Studies of magnesium - hydroxyapatite micro/nano film for drug sustained release."Appl Surf Sci. 2021 Nov;565:150598
16. [IF=4.158] Jinxing Cao et al."In vitro degradation assessment of calcium fluoride-doped hydroxyapatite coating prepared by pulsed laser deposition."Surf Coat Tech. 2021 Jun;416:127177
17. [IF=7.328] Jinxing Cao et al."Osteogenic potential evaluation of biotin combined with magnesium-doped hydroxyapatite sustained-release film."Mat Sci Eng C- Mater. 2022 Jan;:112679

Hydroxylapatite, Fast Flow - Nature

Open Data Verified Data

apatite can be divided into fluorapatite, chlorapatite and hydroxyapatite according to the type of additional anion. Sometimes the additional anion is (C03)2-, which is called carbon apatite, among them, fluorapatite is the most common. Hexagonal crystal system, the crystal is often hexagonal columnar, aggregate block, granular or tuberculosis, etc. Due to different colors containing impurities, there are gray-green, light green, blue-green, blue-purple, light red, red-brown, yellow, etc., pure colorless and transparent, with light green and gray-green more common. Glass gloss, the fracture was oil gloss, White Stripes. Hardness 5, density 3. 18~3.41g/cm3. It is insoluble in water and emits phosphorescence after heating. When rubbing, it emits a burning smell like fur. Apatite is a phosphate mineral widely distributed in the Earth's crust, which can be formed in endogenesis, Exogenesis and metamorphism. About 95% of the phosphorus in nature is concentrated in apatite.

Last Update：2024-01-02 23:10:35

Hydroxylapatite, Fast Flow - Preparation Method

Open Data Verified Data

mining method and process flow are the same as that of phosphorite. Due to the coarse particle size and good floatability of the phosphorus minerals in the apatite ore of magmatic rock type and the phosphate limestone ore of metamorphic rock type, the phosphorus minerals can be directly obtained by the positive flotation method, in addition, the iron minerals in the ore can be recovered by phosphorus separation method. The general beneficiation process is the same as that of phosphorite. The Maying phosphate mine in Chengde city, Hebei province is a magmatic type apatite ore, and its flotation process is one roughing, one sweeping and two selecting; The flotation froth product is a phosphate concentrate; The medium ore is a vanadium-iron concentrate obtained by magnetic separation.

Last Update：2022-01-01 10:58:03

Hydroxylapatite, Fast Flow - Introduction

It was found that hydroxyapatite nanopowders incorporated into biodegradable polymer composites or deposited on biocompatible substrates promote the adhesion and proliferation of bone-forming cells (osteoblasts).
Last Update：2022-10-16 17:13:10

Hydroxylapatite, Fast Flow - Use

Open Data Verified Data

see phosphorite ". In addition, fluorapatite crystals are ideal laser-emitting materials and have been used in phosphate glass lasers; They can also be used as ion exchangers for isotope separation. Phosphate rock associated with vanadium, titanium, iron, rare earth, strontium, uranium, iodine, fluorine and other elements reached a certain content can be comprehensive recycling.

Last Update：2022-01-01 10:58:02

Hydroxylapatite, Fast Flow - Safety

Open Data Verified Data

Same as phosphorite ".

Last Update：2022-01-01 10:58:03

Hydroxylapatite, Fast Flow - Reference Information

EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Hydroxyapatite Hydroxyapatite, also known as hydroxyapatite, is the natural mineralization of calcium apatite (Ca5(PO4)3(OH)). Its molecular formula is Ca5(PO4)3(OH), but it is often written as Ca10(PO4)6(OH)2 to represent the crystal structure composed of two molecules. Hydroxyapatite is a pure positive end element containing hydroxide in apatite. OH-ions can be replaced by fluoride ions, chloride ions or carbonate ions to form fluorapatite or chlorapatite. Hydroxyapatite, abbreviated as HAP, is the most widely used calcium phosphate crystalline phase. Calcium phosphate is the main mineral component of vertebrate bones and teeth. Among calcium phosphate salts, hydroxyapatite is the most thermodynamically stable crystalline phase of calcium phosphate in body fluids, and is most similar to the mineral parts of human bones and teeth. The ratio of calcium and phosphorus in hydroxyapatite is affected by the synthesis mode, and the composition is more complicated if the ratio of calcium to phosphorus is not fixed.
Use Used as fertilizer and feed additive
Hydroxyapatite has a wide range of applications in the following fields due to its unique physical and chemical structure:(1) Application in sewage treatment;(2) Application in remediation of contaminated soil;(3) Application in medicine;(4) Other applications.
Purify protein, separate single-stranded RNA from double-stranded RNA, and purify DNA.
production method 1. fresh animal bones are cleaned and removed, steamed to remove bone glue fat, and then dried and crushed to prepare bone meal.
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-30 12:40:20
Hydroxylapatite, Fast Flow
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CAS: 1306-06-5
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: hydroxylapatite Request for quotation
CAS: 1306-06-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: HAP Visit Supplier Webpage Request for quotation
CAS: 1306-06-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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Hydroxylapatite, Fast Flow
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