Iohexol Impurity 22 - Names and Identifiers
Name | 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate
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Synonyms | Iohexol Impurity 22 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate 5-Amino-N,Na€-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide Tetraacetate
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CAS | 76801-94-0
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Iohexol Impurity 22 - Physico-chemical Properties
Molecular Formula | C22H26I3N3O10
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Molar Mass | 873.17 |
Solubility | Chloroform, Dichloromethane |
Appearance | Solid |
Color | Beige |
Iohexol Impurity 22 - Upstream Downstream Industry
Iohexol Impurity 22 - Introduction
5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate(5-amino-N,N'-bis(2,3-dihydroxypropyl)-2, 4,6-Triiodo -1,3-phthalic acid amide tetraacetate) is a chemical substance with the following properties, uses, preparation methods and safety information:
Nature:
-Appearance: Usually white or off-white crystalline powder
-Molecular weight: about 914.8g/mol
-Melting point: About 220-230 degrees Celsius
-Solubility: Soluble in organic solvents such as methanol and ethanol
Use:
-Medical field: It can be used as an X-ray contrast agent to enhance the contrast of CT scan images and help doctors observe internal organs and blood vessels more clearly
-Chemical field: It can be used as an intermediate in organic synthesis and used to synthesize other compounds
Method:
The preparation method of 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate includes the following steps:
1. Take 2,4, 6-triiodo -1,3-phthalic acid and react with appropriate amount of acetic acid to generate triiodo anhydride.
2. The triiodo anhydride is reacted with 2,3-dihydroxy propanol to generate a polyhydroxy compound.
3. Under basic conditions, a polyhydroxy compound is reacted with an amino compound to give the target product 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate.
Safety Information:
- 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate is a chemical substance that should be stored in a dry, cool place.
-Use should wear appropriate protective equipment, such as laboratory gloves, eye protection glasses, etc.
-Avoid inhalation of dust and contact with skin, eyes and mucous membranes, avoid ingestion.
-In case of contact or inhalation, rinse the area immediately with water and seek medical help.
-Observe the relevant safety procedures and properly store and handle the chemical.
Last Update:2024-04-09 15:18:03