Isopropyl thiourea - Names and Identifiers
Isopropyl thiourea - Physico-chemical Properties
Molecular Formula | C4H10N2S
|
Molar Mass | 118.2 |
Density | 1.051±0.06 g/cm3(Predicted) |
Melting Point | 169-170°C |
Boling Point | 173.8±23.0 °C(Predicted) |
Flash Point | 58.9°C |
Vapor Presure | 1.25mmHg at 25°C |
BRN | 1743052 |
pKa | 14.68±0.70(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.534 |
MDL | MFCD00041375 |
Isopropyl thiourea - Risk and Safety
Risk Codes | 22 - Harmful if swallowed
|
Safety Description | S22 - Do not breathe dust.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
UN IDs | 2811 |
RTECS | YT6125000 |
Packing Group | III |
Isopropyl thiourea - Introduction
Isopropylthiourea is an organic compound with the chemical formula C4H9N3S. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Isopropylthiourea is a colorless to pale yellow solid, sometimes slightly yellow crystalline.
-Solubility: It has low solubility in water, but has better solubility in organic solvents such as ethanol, ether and chloroform.
-Melting point: Isopropylthiourea has a lower melting point, usually between 80-85 degrees Celsius.
Use:
- Isopropylthiourea is widely used as an intermediate for pharmaceuticals, pesticides and rubber additives.
-Pharmaceutical applications: It is commonly used in the field of medicine for the synthesis of cephalosporin antibiotics and some other drugs.
-Pesticide application: Isopropylthiourea is also used to synthesize some high-efficiency pesticides and fungicides in the pesticide manufacturing process.
-Rubber additive: This compound can be used as an accelerator and anti-aging agent in the rubber industry to provide processability and durability.
Method:
- Isopropylthiourea can be prepared by the reaction of acetone and thiourea.
-In the reaction, acetone and thiourea are added to the reaction bottle in a molar ratio of 1:2, and heated to reflux. As the reaction proceeds, the product Isopropylthiourea is gradually formed. After completion of the reaction, the pure product obtained can be purified by crystallization or washing and distillation under reduced pressure.
Safety Information:
- Isopropylthiourea can be considered to be low-toxic under normal circumstances, but it is still necessary to take necessary protective measures when using it.
-It may be irritating to the eyes and skin. Therefore, when using Isopropylthiourea, avoid contact with skin and eyes, and wear appropriate personal protective equipment such as gloves and goggles during operation.
-During storage, it should be placed in a closed container and away from fire and oxidizing agents.
-The handling of Isopropylthiourea should comply with relevant safe operating regulations and follow local regulations and regulations.
Last Update:2024-04-09 20:48:19