L-4-HYDROXYPHENYLGLYCINE
L-(+)-A-4-hydroxyphenylglycine
CAS: 32462-30-9
Molecular Formula: C8H9NO3
L-4-HYDROXYPHENYLGLYCINE - Names and Identifiers
| Name | L-(+)-A-4-hydroxyphenylglycine |
| Synonyms | L-NORTYR H-HPG-OH H-PHG(4-HYDROXY)-OH L-4-HYDROXYPHENYLGLYCINE 4-Hydroxy-L-phenylglycine 4-HYDROXY-L-PHENYLGLYCINE L(+)4-Phydroxyphenylglycine L-(+)-P-HYDROXYPHENYLGLYCINE L-(+)-A-4-hydroxyphenylglycine L-(+)-A-4-HYDROXYPHENYLGLYCINE (S)-2-(4-Hydroxyphenyl)glycine (S)-AMINO-(4-HYDROXY-PHENYL)-ACETIC ACID (2S)-amino(4-hydroxyphenyl)ethanoic acid |
| CAS | 32462-30-9 |
| EINECS | 251-061-7 |
| InChI | InChI=1/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1 |
| InChIKey | LJCWONGJFPCTTL-ZETCQYMHSA-N |
L-4-HYDROXYPHENYLGLYCINE - Physico-chemical Properties
| Molecular Formula | C8H9NO3 |
| Molar Mass | 167.16 |
| Density | 1.396±0.06 g/cm3(Predicted) |
| Melting Point | ~240°C (dec.) |
| Boling Point | 365.8±32.0 °C(Predicted) |
| Specific Rotation(α) | 158 º (c=1% in 1M HCl) |
| Flash Point | 175°C |
| Solubility | Aquous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Water (Slightly) |
| Vapor Presure | 5.4E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| BRN | 3589845 |
| pKa | 2.15±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.633 |
L-4-HYDROXYPHENYLGLYCINE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
L-4-HYDROXYPHENYLGLYCINE - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Biological activity | Oxfenicine (L-p-Hydroxyphenylglycine) is a carnitine palmitoyltransferase -1 inhibitor with oral activity. Oxfenicine can inhibit the oxidation of fatty acids in the heart. Oxfenicine protects the heart from damage to necrotic tissue during ischemia. |
| target | carnitine palmitoyltransferase-1 |
Last Update：2024-04-09 21:32:05
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