L-ARGININE AMIDINOHYDROLASE

L-ARGININE AMIDINOHYDROLASE - Names and Identifiers

Name	ARGINASE
Synonyms	ARGINASE L-ARGINASE LIVER, BOVINE L-ARGININE AMIDINASE L-ARGINASE, BEEF LIVER L-ARGININE AMIDINOHYDROLASE L-ARGINNINE AMIDINA-HYDROLASE L-ARGININE AMIDINASE (BOVINE LIVER)
CAS	9000-96-8
EINECS	232-570-3

L-ARGININE AMIDINOHYDROLASE - Physico-chemical Properties

Solubility	Soluble in water
Storage Condition	-20℃

L-ARGININE AMIDINOHYDROLASE - Reference

Reference

1. [IF=3.5] Jiakun Shen et al."Mogroside V exerts anti-inflammatory effects on fine particulate matter-induced inflammation in porcine alveolar macrophages."Toxicol In Vitro. 2022 Apr;80:105326

L-ARGININE AMIDINOHYDROLASE - Vitality definition

One unit will cause the hydrolysis of 1.0 μmole of L-arginine per minute at pH 9.5 and 37 °C。

Last Update：2023-08-16 21:32:38

L-ARGININE AMIDINOHYDROLASE - Introduction

The quarternary structure of native rat liver arginase has been described by Hirsch-Kolb, H & Greenberg, D.M.," Molecular characterisitics of rat liver arginase", J. Biol Chem., 243, 6123-6129 and Baranczyk-Kuzma A., Porembska Z. & Mochnacka, I., Acta Biochim Polon, 23, 151-163. EDTA treatment dissociated the enzyme into inactive subunits of 30,000 daltons each. Addition of Mn2+ ions restored the activity and caused reassociation of subunits to the natve form of 120,000 daltons.

Last Update：2023-08-16 21:32:38

L-ARGININE AMIDINOHYDROLASE - Nature

storage conditions	-20°C
morphology	powder
color	slightly yellow
EPA chemical information	Arginase (9000-96-8)

Last Update：2024-04-10 22:43:14

L-ARGININE AMIDINOHYDROLASE - Physiological effects

Studies have found that up-regulation of arginase has a great impact on vascular function and is one of the causes of vascular dysfunction, but the mechanism of up-regulation is still unclear and may include the participation of multiple mediators. The activation of arginase by cysteine-iron is dose-dependent, accompanied by the formation of • OH free radicals. Interestingly, when the production of • OH is inhibited by salicylic acid derivatives and superoxide dismutase, the activity of arginase is also correspondingly inhibited, suggesting that • OH free radicals may be involved in the activation of arginase. Cytokines such as IL-4 and IL-13 can up-regulate the expression of arginase I, and supplement of exogenous arginine can restore the ability of IL-4 treated macrophages to produce NO. H2O2 can also up-regulate arginase expression, thereby inhibiting NO-mediated endothelium-dependent coronary artery dilatation. At present, there are few researches on the signaling pathway regulating arginase expression in vascular cells.

Last Update：2024-04-10 22:29:15

L-ARGININE AMIDINOHYDROLASE - WGK Germany 3 F 10-21

WGK Germany	3
F	10-21

Last Update：2024-04-10 22:29:15

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L-ARGININE AMIDINOHYDROLASE

ARGINASE

CAS: 9000-96-8

Molecular Formula:

L-ARGININE AMIDINOHYDROLASE - Names and Identifiers

L-ARGININE AMIDINOHYDROLASE - Physico-chemical Properties

L-ARGININE AMIDINOHYDROLASE - Reference

L-ARGININE AMIDINOHYDROLASE - Vitality definition

L-ARGININE AMIDINOHYDROLASE - Introduction

L-ARGININE AMIDINOHYDROLASE - Nature

L-ARGININE AMIDINOHYDROLASE - Physiological effects

L-ARGININE AMIDINOHYDROLASE - WGK Germany 3 F 10-21

Supplier List

L-ARGININE AMIDINOHYDROLASE Request for Quotation

ARGINASE

CAS: 9000-96-8

Molecular Formula:

L-ARGININE AMIDINOHYDROLASE - Names and Identifiers

L-ARGININE AMIDINOHYDROLASE - Physico-chemical Properties

L-ARGININE AMIDINOHYDROLASE - Reference

L-ARGININE AMIDINOHYDROLASE - Vitality definition

L-ARGININE AMIDINOHYDROLASE - Introduction

L-ARGININE AMIDINOHYDROLASE - Nature

L-ARGININE AMIDINOHYDROLASE - Physiological effects

L-ARGININE AMIDINOHYDROLASE - WGK Germany 3 F 10-21

Supplier List

L-ARGININE AMIDINOHYDROLASE