L-ASPARAGINE TERT-BUTYL ESTER
H-Asn-OtBu
CAS: 25456-86-4
Molecular Formula: C8H16N2O3
L-ASPARAGINE TERT-BUTYL ESTER - Names and Identifiers
| Name | H-Asn-OtBu |
| Synonyms | L-Asn-Otbu H-ASN-OBUT H-Asn-OtBu tert-butyl asparaginate tert-butyl L-asparaginate Asparagine tert-butyl ester L-asparagine Tert-butyl ester L-ASPARAGINE TERT-BUTYL ESTER L-Asparagine tert-butyl ester tert-Butyl 2,4-diamino-4-oxobutanoate tert-butyl (2S)-2,4-diamino-4-oxobutanoate |
| CAS | 25456-86-4 |
| InChI | InChI=1/C8H16N2O3/c1-8(2,3)13-7(12)5(9)4-6(10)11/h5H,4,9H2,1-3H3,(H2,10,11)/t5-/m0/s1 |
L-ASPARAGINE TERT-BUTYL ESTER - Physico-chemical Properties
| Molecular Formula | C8H16N2O3 |
| Molar Mass | 188.22 |
| Density | 1.113±0.06 g/cm3(Predicted) |
| Boling Point | 340.2±32.0 °C(Predicted) |
| Flash Point | 168°C |
| Vapor Presure | 8.76E-05mmHg at 25°C |
| Appearance | Crystallization |
| pKa | 16.01±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.478 |
L-ASPARAGINE TERT-BUTYL ESTER - Risk and Safety
| Risk Codes | 52 - Harmful to aquatic organisms |
L-ASPARAGINE TERT-BUTYL ESTER - Introduction
H-Asn-OtBu(H-Asn-OtBu) is an amino acid protecting group commonly used in peptide synthesis and biochemical studies. Here is the relevant information:
Nature:
1. Appearance: colorless or light yellow liquid.
2. Molecular formula: C11H21NO4.
3. Molecular weight: 235.29g/mol.
4. Melting point:-17 to -15 ℃.
5. Boiling point: About 240 ℃.
6. Stable at room temperature.
Use:
1. H-Asn-OtBu is a common protecting group for synthetic peptides, which can protect the amino groups in amino acids.
2. As a raw material for the synthesis of peptides such as hexapeptide.
Method:
H-Asn-OtBu can be prepared by the following steps:
1. L-Aspartic acid and T-butanol are added to the reaction solvent.
2. Add an acidic catalyst, such as dimethyl sulfate.
3. The reaction is carried out at an appropriate temperature and reaction time.
4. Distilling the reaction solution to obtain a H-Asn-OtBu.
Safety Information:
1. The H-Asn-OtBu is a chemical and should follow the corresponding safety operation procedures.
2. May be irritating to the eyes, skin or respiratory system, wear personal protective equipment when using.
3. Avoid contact with fire, avoid inhalation of steam.
4. Store in a cool, dry place, away from heat sources and oxidants.
5. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Nature:
1. Appearance: colorless or light yellow liquid.
2. Molecular formula: C11H21NO4.
3. Molecular weight: 235.29g/mol.
4. Melting point:-17 to -15 ℃.
5. Boiling point: About 240 ℃.
6. Stable at room temperature.
Use:
1. H-Asn-OtBu is a common protecting group for synthetic peptides, which can protect the amino groups in amino acids.
2. As a raw material for the synthesis of peptides such as hexapeptide.
Method:
H-Asn-OtBu can be prepared by the following steps:
1. L-Aspartic acid and T-butanol are added to the reaction solvent.
2. Add an acidic catalyst, such as dimethyl sulfate.
3. The reaction is carried out at an appropriate temperature and reaction time.
4. Distilling the reaction solution to obtain a H-Asn-OtBu.
Safety Information:
1. The H-Asn-OtBu is a chemical and should follow the corresponding safety operation procedures.
2. May be irritating to the eyes, skin or respiratory system, wear personal protective equipment when using.
3. Avoid contact with fire, avoid inhalation of steam.
4. Store in a cool, dry place, away from heat sources and oxidants.
5. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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Product Name: H-Asn-OtBu Request for quotation
CAS: 25456-86-4
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Mobile: +86-18980427282
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CAS: 25456-86-4
Tel: +86-18980427282
Email: hk999@hengkangtech.com
Mobile: +86-18980427282
QQ: 1525088774
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