L-Glutamic acid dibenzyl ester 4-toluenesulfonate

L-Glutamic acid dibenzyl ester 4-toluenesulfonate - Names and Identifiers

Name	H-Glu(OBzl)-OBzl.p-tosylate
Synonyms	GLU(OBZL)-OBZL TOS H-Glu(OBzl)-OBzl Tos Glu(OBzl)-OBzl·TosOH L-Glu(OBzl)-OBzl·TosOH H-Glu(OBzl)-OBzl.TosOH H-Glu(obzl)-obzl-tos H-Glu(OBzl)-OBzl·TosOH O,O'-Dibenzyl-L-glutamine L-(g-O-Bzl)-Glu-OBzl TsOH H-GLU(OBZL)-OBZL 4-TOSYLATE H-GLU(OBZL)-OBZL P-TOSYLATE H-Glu(OBzl)-OBzl.p-tosylate GLUTAMIC ACID(OBZL)-OBZL P-TOSYLATE L-GLUTAMIC ACID DIBENZYL ESTER-P-TOSYLATE O,O'-dibenzyl-L-glutamine toluene-p-sulphonate L-Glutamic acid dibenzyl ester 4-toluenesulfonate (2S)-1,5-bis(benzyloxy)-1,5-dioxopentan-2-aminium 4-methylbenzenesulfonate
CAS	2791-84-6
EINECS	220-522-4
InChI	InChI=1/C19H21NO4.C7H8O3S/c20-17(19(22)24-14-16-9-5-2-6-10-16)11-12-18(21)23-13-15-7-3-1-4-8-15;1-6-2-4-7(5-3-6)11(8,9)10/h1-10,17H,11-14,20H2;2-5H,1H3,(H,8,9,10)/t17-;/m0./s1

L-Glutamic acid dibenzyl ester 4-toluenesulfonate - Physico-chemical Properties

Molecular Formula	C26H29NO7S
Molar Mass	499.58
Melting Point	142 °C
Boling Point	453.5°C at 760 mmHg
Flash Point	165.6°C
Solubility	DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
Vapor Presure	2.06E-08mmHg at 25°C
Appearance	Powder
Color	White to Off-White
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

L-Glutamic acid dibenzyl ester 4-toluenesulfonate - Introduction

H-Glu(OBzl)-OBzl.p-H-Glu(OBzl)-OBzl.p-tosylate) is a compound commonly used in organic synthesis. Here are details about the compound:

Nature:
H-Glu(OBzl)-OBzl.p-tosylate is a white solid with a high melting point. It is a crystalline solid which is readily soluble in organic solvents such as ethanol and methyl dimethylferroferrite.

Use:
H-Glu(OBzl)-OBzl.p-tosylate is mainly used as a protecting group in organic synthesis to protect the hydroxyl and amino groups of glutamic acid to prevent non-specific reactions in other reactions. It is commonly used in the introduction of amines and in the synthesis of peptides. In addition, it is also used in the synthesis of modified hormonal drugs and chemical development inhibitors.

Method:
The common method for preparing H-Glu(OBzl)-OBzl.p-tosylate is to react L-glutamic acid dibenzyl ester with p-toluenesulfonic acid. The reaction is generally carried out in a simple organic solvent, such as an alcohol or a ketone.

Safety Information:
H-Glu(OBzl)-OBzl.p-tosylate is relatively stable under normal operating conditions. However, it is still necessary to take appropriate safety measures, such as wearing appropriate personal protective equipment (such as gloves and glasses) and operating in a well-ventilated area. In addition, inhalation and skin contact should be avoided. When using or handling the compound, care should be taken to comply with regulations for safe handling and proper disposal of waste.

Last Update：2024-04-09 20:52:54