L-Homoserine lactone hydrochloride
(S)-(+)-α-amino-γ-butyrolactone hydrochloride
CAS: 2185-03-7
Molecular Formula: C4H8ClNO2
L-Homoserine lactone hydrochloride - Names and Identifiers
| Name | (S)-(+)-α-amino-γ-butyrolactone hydrochloride |
| Synonyms | HSL L-Homoserine Lactone HCl HOMOSERINE(L-) LACTONE HCL HOMOSERINE LACTONE HYDROCHLORIDE L-HOMOSERINE LACTONE HYDROCHLORIDE L-(-)-HOMOSERINE LACTONE HYDROCHLORIDE 2-oxo-2,3-dihydrofuran-3-aminium chloride L-(-)-A-AMINO-G-BUTYROLACTONE HYDROCHLORIDE (S)-(+)-α-amino-γ-butyrolactone hydrochloride (3S)-3-aminodihydrofuran-2(3H)-one hydrochloride |
| CAS | 2185-03-7 |
| EINECS | 218-571-1 |
| InChI | InChI=1/C4H5NO2.ClH/c5-3-1-2-7-4(3)6;/h1-3H,5H2;1H |
| InChIKey | XBKCXPRYTLOQKS-DFWYDOINSA-N |
L-Homoserine lactone hydrochloride - Physico-chemical Properties
| Molecular Formula | C4H8ClNO2 |
| Molar Mass | 137.56 |
| Melting Point | 210-220°C (dec.)(lit.) |
| Boling Point | 316.4°C at 760 mmHg |
| Specific Rotation(α) | -25 º (c=0.5, water) |
| Flash Point | 168.8°C |
| Water Solubility | soluble |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Vapor Presure | 0.000411mmHg at 25°C |
| Appearance | Solid |
| Color | White to Pale Beige |
| BRN | 3562187 |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | -26 ° (C=0.2, H2O) |
L-Homoserine lactone hydrochloride - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29322090 |
L-Homoserine lactone hydrochloride - Reference Information
| Uses | L-homoserine lactone hydrochloride is widely used as an important intermediate in organic synthesis and is also an important intermediate for the synthesis of chiral herbicide L-glufosinate. |
| Preparation | It can be prepared from the natural amino acid L-methionine. The commonly used three-step method is to first use methyl iodide and L-Methionine reacts to form onium salt, then it is converted into L-homoserine under alkaline conditions, and finally dehydrated under acidic conditions to form L-homoserine lactone hydrochloride. This method has many separation steps. In order to reduce the process, some studies have tried to synthesize the "one-pot method" without separating the intermediate product, and the final product is not purified until the last step. |
Last Update：2024-04-09 21:11:58
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