L-proline, 4-fluoro-, (4S)- - Names and Identifiers
Name | (2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid
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Synonyms | (4S)-4-Fluor-L-prolin (4S)-4-Fluoro-L-proline (2S,4S)-4-fluoro-2-proline L-proline, 4-fluoro-, (4S)- (2S,4S)-4-Fluoro-2-pyrrolidinecarboxylic acid (2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid (2S,4S)-4-Fluoro-Pyrrolidine-2-Carboxylic Acid rel-((2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid),labeled with tritium
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CAS | 6745-32-0
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InChI | InChI=1/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4-/m0/s1 |
L-proline, 4-fluoro-, (4S)- - Physico-chemical Properties
Molecular Formula | C5H8FNO2
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Molar Mass | 133.12 |
Density | 1.309g/cm3 |
Boling Point | 265.108°C at 760 mmHg |
Flash Point | 114.133°C |
Vapor Presure | 0.003mmHg at 25°C |
Appearance | Colorless solid |
Storage Condition | Room Temprature |
Refractive Index | 1.473 |
L-proline, 4-fluoro-, (4S)- - Introduction
(2S,4S)-acid, also known as (2S,4S)-+ acid, is an organic compound. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Usually a white solid.
-Molecular formula: C, H, NO, F
-Molecular weight: 131.11g/mol
-melting point: about 138-140 ℃
-Boiling point: about 297 ℃ (calculated)
-Solubility: Soluble in water, soluble in organic solvents.
Use:
- (2S,4S)-acid can be used as catalysts, synthetic intermediates and organic chemical reagents.
-It is often used in chiral synthesis reactions, as a catalyst to participate in the change of symmetry, to achieve the purpose of producing chiral compounds.
Preparation Method:
- (2S,4S)-acid can be prepared by a variety of synthetic routes, one of which is the reaction of fluorinated 4-bromopyrrolidine with formic acid to obtain the target product.
Safety Information:
-This compound may be harmful to the human body, such as irritation and sensitization.
-Pay attention to safe operation when using, such as wearing protective gloves and glasses, to ensure that the operation is under good ventilation conditions.
-In case of contact with skin or eyes, rinse immediately with water.
-Store and handle the compound properly to avoid contact with strong oxidants and combustibles.
Please note that before using or handling any chemicals, please read and follow relevant safety guidelines and operating procedures to ensure safety and correctness.
Last Update:2024-04-10 22:29:15