Name | LCZ 696 Impurity B |
Synonyms | LCZ 696 Impurity B (2R,4R)-Sacubitril Sacubitril Impurity B Sacubitril Impurity 24 LCZ-696 Impurity 7 calcium salt Sacubitril-(2R, 4R)-Isomer Calcium Salt [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, 4-ethyl ester, (αR,γR)-rel- |
CAS | 766480-48-2 |
Molecular Formula | C24H29NO5 |
Molar Mass | 411.49076 |
Density | 1.151±0.06 g/cm3(Predicted) |
Boling Point | 656.9±55.0 °C(Predicted) |
pKa | 4.72±0.10(Predicted) |
Storage Condition | -20°C |
Physical and Chemical Properties | Bioactive 2R,4R-Sacubitril is a Sacubitri impurity. In animal models, Sacubitril and valsartan are combined for related studies on remission of heart failure. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.43 ml | 12.151 ml | 24.302 ml |
5 mM | 0.486 ml | 2.43 ml | 4.86 ml |
10 mM | 0.243 ml | 1.215 ml | 2.43 ml |
5 mM | 0.049 ml | 0.243 ml | 0.486 ml |