LG-100064

Name	4-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalene-2-carbonyl)benzoic acid
Synonyms	LG-100064 4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl) 4-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalene-2-carbonyl)benzoic acid 4-(3,5,5,8,8-pentaMethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-phthalenyl)carbonyl]benzoic acid 4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)benzoic acid 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic acid Benzoic acid, 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]-
CAS	153559-46-7

Molecular Formula	C23H26O3
Molar Mass	350.45
Density	1.095
Melting Point	198-199 °C
Boling Point	491.4±45.0 °C(Predicted)
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Sl
Appearance	Solid
Color	White to Off-White
pKa	3.74±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Irritant
MDL	MFCD13191327
In vitro study	LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC 50 s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ. LG-100064 shows no effect on RARα/β/γ (EC 50 , >10000 nM).

biological activity	LG-100064 is a kind of retinol X receptor (retinoid-X-receptor (RXR)) agonist, and the EC50 values for RXRα,RXRβ and RXRγ are 330 nM,200 nM and 260 nM respectively; LG-100064 can be used for cancer research.
target	EC50: 330 nM (RXRα), 200 nM (RXRβ), 260 nM (RXRγ)
in vitro study	LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC 50 s of 330 nM, 200 nM, and 260 nM for RXR α, RXRβ and RXRγ. LG-100064 shows no effect on RARα/β/γ (EC 50 , >10000 nM).

Last Update：2024-04-09 21:11:58