Lincomycin 2-Phosphate, Clindamycin phosphate Impurity F - Names and Identifiers
Lincomycin 2-Phosphate, Clindamycin phosphate Impurity F - Physico-chemical Properties
Molecular Formula | C18H35N2O9PS
|
Molar Mass | 486.52 |
Density | 1.42±0.1 g/cm3(Predicted) |
Melting Point | >208°C (dec.) |
Solubility | Methanol (Slightly, Heated), Water (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 1.83±0.10(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Lincomycin 2-Phosphate, Clindamycin phosphate Impurity F - Introduction
Lincomycin 2-Phosphate (Lincomycin 2-Phosphate) is a pesticide and a broad-spectrum penicillin antibiotic. It is the hydrochloride salt obtained from lincomycin by reaction with phosphoric acid.
Lincomycin 2-phosphate has antibacterial activity and can be used to prevent and treat infectious diseases in animals. It has a good inhibitory effect on Gram-positive bacteria and certain Gram-negative bacteria, in particular on Streptococcus pneumoniae, Staphylococcus aureus and Streptococcus strains.
The preparation method of lincomycin 2-phosphate mainly includes two steps: first, lincomycin is reacted with tartaric acid to obtain lincomycin tartrate, and then lincomycin tartrate is reacted with phosphoric acid to form lincomycin 2-phosphate.
The safety of lincomycin 2-phosphate is high, but it is still necessary to follow certain safety procedures. Avoid contact with skin and eyes during use, and take good ventilation measures. At the same time, lincomycin 2-phosphate has certain toxicity to the human body and the environment, so it is necessary to strictly control the dosage and concentration in the production and use process, and comply with relevant regulations and safety operation guidelines.
Last Update:2024-04-09 21:11:58